Aconitase 1 Antikörper
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- Target Alle Aconitase 1 (ACO1) Antikörper anzeigen
- Aconitase 1 (ACO1)
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Aconitase 1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- Affinity purification
- Immunogen
- Synthetic peptide of human ACO1
- Isotyp
- IgG
- Top Product
- Discover our top product ACO1 Primärantikörper
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- Applikationshinweise
- WB 1:1000-1:5000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.2 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- Konservierungsmittel
- Sodium azide
- Handhabung
- Avoid freeze / thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Aconitase 1 (ACO1)
- Andere Bezeichnung
- ACO1 (ACO1 Produkte)
- Synonyme
- ACONS antikoerper, IREB1 antikoerper, IREBP antikoerper, IREBP1 antikoerper, IRP1 antikoerper, Acon1 antikoerper, Ratireb antikoerper, ratireb antikoerper, Aco1 antikoerper, AI256519 antikoerper, Aco-1 antikoerper, Irebp antikoerper, Irp1 antikoerper, aconitase 1 antikoerper, aconitase 1, soluble antikoerper, aconitase 1 L homeolog antikoerper, ACO1 antikoerper, Aco1 antikoerper, aco1.L antikoerper
- Hintergrund
- Aconitase 1, also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs). IREs are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. The iron-induced binding to the IRE results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA. Thus, IREB1 plays a central role in cellular iron homeostasis. It was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes.
- Molekulargewicht
- Calculated MW: 98 kDa
- NCBI Accession
- NP_002188
- Pathways
- Transition Metal Ion Homeostasis
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