NUP153 Antikörper (AA 610-1191)

Produktnummer ABIN2452062

Produktdetails anti-NUP153 Antikörper

Target: NUP153 (Nucleoporin 153kDa (NUP153))

Bindungsspezifität: AA 610-1191

Reaktivität: Ratte

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser NUP153 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: Specific to human, mouse, rat and monkey Nup153 proteins.

Kreuzreaktivität (Details): Not tested for other species

Produktmerkmale: When injected into the nucleus,R4C8 accumulates into the nuclear pores of Hela cells. R4C8 works in immuno-cytochemistry very well.

Aufreinigung: Purified

Sterilität: Sterile filtered

Immunogen: Recombinant GST-fused rat Nup153 (610-1191aa, Zn finger and FG repeats domain)

Klon: R4C8

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: 1. Western blotting: 160 kDa single band in Hela cell extract
2. Immunocytochemistry
3. ELISA
Other applications have not been tested.

Additional comments:
When injected into the nucleus, R4C8 accumulates into the nuclear pores of Hela cells.
R4C8 works in immuno-cytochemistry very well.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Upon receipt aliquot and store at -20 C

Referenzen für anti-NUP153 Antikörper (ABIN2452062)

Lim, Fahrenkrog, Köser, Schwarz-Herion, Deng, Aebi: "Nanomechanical basis of selective gating by the nuclear pore complex." in: Science (New York, N.Y.), Vol. 318, Issue 5850, pp. 640-3, (2007) (PubMed).

Ullman, Shah, Powers, Forbes: "The nucleoporin nup153 plays a critical role in multiple types of nuclear export." in: Molecular biology of the cell, Vol. 10, Issue 3, pp. 649-64, (1999) (PubMed).

Details zu NUP153

Target: NUP153 (Nucleoporin 153kDa (NUP153))

Andere Bezeichnung: Nup153 (NUP153 Produkte)

Synonyme: CG4453 antikoerper, Dmel\\CG4453 antikoerper, NUP153 antikoerper, Nup 153 antikoerper, dNup153 antikoerper, dmNup153 antikoerper, nup153 antikoerper, NUCZINK antikoerper, B130015D15Rik antikoerper, C88147 antikoerper, HNUP153 antikoerper, N153 antikoerper, Nucleoporin 153kD antikoerper, nucleoporin 153 antikoerper, nucleoporin 153kDa L homeolog antikoerper, Nup153 antikoerper, NUP153 antikoerper, nup153.L antikoerper

Hintergrund: The nuclear pore complex (NPC) regulates cargo transport between the cytoplasm and the nucleus. Nup (Nucleoporin) 153 is a large (153 kDa) O-linked glycoprotein which is a component of the basket structure located on the nucleoplasmic face of NPC. Nup153 plays a critical role in nuclear export of RNA and proteins. The antibody was purified from the serum-free cultured medium of the hybridoma under mild conditions by propriety chromatography processes.

UniProt: P49790

Pathways: Protein targeting to Nucleus