NUP62 Antikörper (Phenylalanine-Glycine Repeat)

Produktnummer ABIN2452063

Produktdetails anti-NUP62 Antikörper

Target: NUP62 (Nucleoporin 62kDa (NUP62))

Bindungsspezifität: AA 1-179, Phenylalanine-Glycine Repeat

Reaktivität: Human, Affe

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser NUP62 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Spezifität: Specific to human (HeLa cells) and simian (Cos cells). The antibody did not react with mouse.

Aufreinigung: Purified from serum-free culture medium of the hybridoma by proprietary chromatography under mild conditions.

Sterilität: Sterile filtered

Immunogen: Recombinant human Nup62 (amino acids 1-300) (GST-Nup62-His)

Klon: 2A

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: 1. Western blotting: 1/500 ~1/2,000 dilution
2. Immunoprecipitation (assay dependent)
3. Immunofluorescece / Immunocytochemistry: 1/400)
4. ELISA (assay dependent)
5. When this antibody was micro-injected into the cytoplasm of the HeLa cells, it accumulates into the nuclear pores as examined by immunofluorescence staining. .

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS (x1), 50 % glycerol. Azide and carrier free.

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Upon arrival centrifuge briefly and store at -20 C.

Referenzen für anti-NUP62 Antikörper (ABIN2452063)

Fukuhara, Sakaguchi, Katahira, Yoneda, Ogino, Tachibana: "Functional analysis of nuclear pore complex protein Nup62/p62 using monoclonal antibodies." in: Hybridoma (2005), Vol. 25, Issue 2, pp. 51-9, (2006) (PubMed).

Maeshima, Yahata, Sasaki, Nakatomi, Tachibana, Hashikawa, Imamoto, Imamoto: "Cell-cycle-dependent dynamics of nuclear pores: pore-free islands and lamins." in: Journal of cell science, Vol. 119, Issue Pt 21, pp. 4442-51, (2006) (PubMed).

Details zu NUP62

Target: NUP62 (Nucleoporin 62kDa (NUP62))

Andere Bezeichnung: Nup62 (NUP62 Produkte)

Synonyme: IBSN antikoerper, SNDI antikoerper, p62 antikoerper, NUP62 antikoerper, AA589433 antikoerper, AI426861 antikoerper, AI790512 antikoerper, AU045898 antikoerper, D7Ertd649e antikoerper, Nupc1 antikoerper, CG6251 antikoerper, Dmel\\CG6251 antikoerper, DDBDRAFT_0167902 antikoerper, DDBDRAFT_0237712 antikoerper, DDB_0167902 antikoerper, DDB_0237712 antikoerper, nup62 antikoerper, Np62 antikoerper, nucleoporin 62 antikoerper, hypothetical protein antikoerper, nucleoporin 62kDa antikoerper, Nucleoporin 62kD antikoerper, predicted protein antikoerper, nuclear pore protein antikoerper, Nup62 nuclear pore complex glycoprotein p62-related protein (IC) antikoerper, Nuclear pore glycoprotein p62 antikoerper, NUP62 antikoerper, PGTG_03077 antikoerper, Nup62 antikoerper, nup62 antikoerper

Hintergrund: The nuclear pore complex (NPC) regulates cargo transport between the cytoplasm and the nucleus. Nucleoporins are the main components of the NPC in eukaryotic cells. Nup (Nucleoporin) 62 (522 aa, 53 kDa) is a member of the FG-repeat containing nucleoporins and is localized to the NPC central plug. Nup62 associates with the importin alpha/beta complex which is involved in the import of proteins containing nuclear localization signals. Predicted to contain about 10 N-acetylglucosamine side chain .

UniProt: P37198

Pathways: EGFR Signaling Pathway, SARS-CoV-2 Protein Interaktom