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PRNP Antikörper

PRNP Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 2C5-5 unconjugated
Produktnummer ABIN2452080
  • Target Alle PRNP Antikörper anzeigen
    PRNP (Prion Protein (PRNP))
    Reaktivität
    • 83
    • 33
    • 25
    • 12
    • 11
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 84
    • 15
    • 2
    • 1
    Maus
    Klonalität
    • 77
    • 25
    Monoklonal
    Konjugat
    • 44
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser PRNP Antikörper ist unkonjugiert
    Applikation
    • 51
    • 30
    • 27
    • 26
    • 17
    • 14
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA
    Kreuzreaktivität (Details)
    Does not react with mouse Prion. Not tested with other species
    Aufreinigung
    Purified
    Sterilität
    Sterile filtered
    Immunogen
    Recombinant human PrP lacking GPI anchor expressed and purified from rabbit kidney cell line RK13
    Klon
    2C5-5
    Isotyp
    IgG
    Top Product
    Discover our top product PRNP Primärantikörper
  • Applikationshinweise
    1) Western blotting: ~0. 5 g/mL
    2) ELISA (most suitable)
    Other applications have not been tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS, 50 % glycerol
    Konservierungsmittel
    Azide free
    Lagerung
    -20 °C
  • Sakudo, Nakamura, Ikuta, Onodera: "Recent developments in prion disease research: diagnostic tools and in vitro cell culture models." in: The Journal of veterinary medical science / the Japanese Society of Veterinary Science, Vol. 69, Issue 4, pp. 329-37, (2007) (PubMed).

  • Target
    PRNP (Prion Protein (PRNP))
    Andere Bezeichnung
    Prion Protein (PRNP Produkte)
    Synonyme
    ASCR antikoerper, AltPrP antikoerper, CD230 antikoerper, CJD antikoerper, GSS antikoerper, KURU antikoerper, PRIP antikoerper, PrP antikoerper, PrP27-30 antikoerper, PrP33-35C antikoerper, PrPc antikoerper, p27-30 antikoerper, Prn antikoerper, Prn-p antikoerper, prp antikoerper, cjd antikoerper, prion antikoerper, prp(c) antikoerper, MGC84114 antikoerper, PRP antikoerper, PRPC antikoerper, Prp antikoerper, SIP antikoerper, PRNP antikoerper, AA960666 antikoerper, AI325101 antikoerper, PrP antikoerper, PrPC antikoerper, PrPSc antikoerper, Prn-i antikoerper, Sinc antikoerper, prP27-30 antikoerper, prP33-35C antikoerper, PrP-1 antikoerper, PrP1 antikoerper, prnprs1 antikoerper, stPrP-1 antikoerper, zgc:123004 antikoerper, prion protein antikoerper, prion protein S homeolog antikoerper, prion protein b antikoerper, PRNP antikoerper, Prnp antikoerper, prnp.S antikoerper, prnpb antikoerper
    Hintergrund
    Prion protein PrP is a membrane glycosylphosphatidylinositol(GPI) anchored glycoprotein highly expressed in neuron and glia cells as well as immune and reproductive cells. Mutations in the octapeptide repeat regions as well as elsewhere in this gene have been associated with neurodegenerative diseases such as Creutzfeldt Jakob disease, fatal familial insomnia, Gerstmann Straussler disease, Huntington disease like 1, and kuru. The infectious isoform of PrPC, known as PrPSc, is able to convert normal PrPPC proteins into the infectious isoform, which is insoluble amyloid aggregate, by changing their. Mature PrP protein in human consists of 209 amino acids. Several forms exist, one cell surface form anchored via and two forms, therefore multiple bands are observed in SDS-PAGE (Figure). conformation topological glycolipid transmembrane
    UniProt
    P04156
    Pathways
    Transition Metal Ion Homeostasis, Activated T Cell Proliferation
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