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RAD18 Antikörper (C-Term)

RAD18 Reaktivität: Human WB, ELISA, IF, IP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2452086
  • Target Alle RAD18 Antikörper anzeigen
    RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))
    Bindungsspezifität
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 50
    • 26
    • 22
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 43
    • 7
    Kaninchen
    Klonalität
    • 37
    • 13
    Polyklonal
    Konjugat
    • 32
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser RAD18 Antikörper ist unkonjugiert
    Applikation
    • 28
    • 16
    • 8
    • 8
    • 7
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)
    Kreuzreaktivität (Details)
    Not reactive to mouse Rad18
    Aufreinigung
    Affinity purified with His-tagged Rad18 protein affinity column
    Immunogen
    GST-fusion protein containing 113 carboxyl terminal of human Rad18
    Isotyp
    IgG
    Top Product
    Discover our top product RAD18 Primärantikörper
  • Applikationshinweise
    1) Western blotting: 1,000 fold dilution
    2) Indirect immunofluorescence staining
    3) Immunoprecipitation
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS, 50 % glycerol
    Konservierungsmittel
    Azide free
    Lagerung
    -20 °C
  • Watanabe, Tateishi, Kawasuji, Tsurimoto, Inoue, Yamaizumi: "Rad18 guides poleta to replication stalling sites through physical interaction and PCNA monoubiquitination." in: The EMBO journal, Vol. 23, Issue 19, pp. 3886-96, (2004) (PubMed).

    Miyase, Tateishi, Watanabe, Tomita, Suzuki, Inoue, Yamaizumi: "Differential regulation of Rad18 through Rad6-dependent mono- and polyubiquitination." in: The Journal of biological chemistry, Vol. 280, Issue 1, pp. 515-24, (2004) (PubMed).

    Tateishi, Sakuraba, Masuyama, Inoue, Yamaizumi: "Dysfunction of human Rad18 results in defective postreplication repair and hypersensitivity to multiple mutagens." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 14, pp. 7927-32, (2000) (PubMed).

  • Target
    RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))
    Andere Bezeichnung
    Rad18 (RAD18 Produkte)
    Synonyme
    RNF73 antikoerper, 2810024C04Rik antikoerper, Rad18sc antikoerper, zgc:55577 antikoerper, RAD18 antikoerper, DDBDRAFT_0218120 antikoerper, DDBDRAFT_0304878 antikoerper, DDB_0218120 antikoerper, DDB_0304878 antikoerper, DKFZp469H0810 antikoerper, RAD18, E3 ubiquitin protein ligase antikoerper, RAD18 E3 ubiquitin protein ligase antikoerper, E3 ubiquitin-protein ligase RAD18 antikoerper, E3 ubiquitin-protein ligase antikoerper, DNA repair protein and ATPase antikoerper, C3HC4-type zinc finger-containing protein antikoerper, RAD18 antikoerper, Rad18 antikoerper, rad18 antikoerper
    Hintergrund
    The Rad6-Rad18 pair of genes plays a critical role in post-replication repair of damaged DNA. Rad6 protein functions as an E2 enzyme and Rad18 (495 aa, 56 kDa) as an ubiquitine ligase (E3) which ubiquitinates PCNA. Rad18 recruits translesion DNA polymerases to damaged DNA.
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