RAD18 Antikörper (C-Term)
(3 Referenzen)-
- Target Alle RAD18 Antikörper anzeigen
- RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))
-
Bindungsspezifität
- C-Term
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser RAD18 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)
- Kreuzreaktivität (Details)
- Not reactive to mouse Rad18
- Aufreinigung
- Affinity purified with His-tagged Rad18 protein affinity column
- Immunogen
- GST-fusion protein containing 113 carboxyl terminal of human Rad18
- Isotyp
- IgG
- Top Product
- Discover our top product RAD18 Primärantikörper
-
anti-E3 ubiquitin-protein ligase RAD18 (RAD18) (AA 332-430) antibody
RAD18 Reaktivität: Human WB, ELISA, IF, IHC (p), RNAi Wirt: Maus Monoclonal 3H7 unconjugated
anti-E3 ubiquitin-protein ligase RAD18 (RAD18) (AA 1-495) antibodyRAD18 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-E3 ubiquitin-protein ligase RAD18 (RAD18) (AA 332-430) antibodyRAD18 Reaktivität: Human ELISA, FACS Wirt: Maus Monoclonal 2G8C10 unconjugated
anti-E3 ubiquitin-protein ligase RAD18 (RAD18) (AA 216-495) antibodyRAD18 Reaktivität: Human WB, IF, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-E3 ubiquitin-protein ligase RAD18 (RAD18) (AA 1-495) antibodyRAD18 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-E3 ubiquitin-protein ligase RAD18 (RAD18) (Internal Region) antibodyRAD18 Reaktivität: Human, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-E3 ubiquitin-protein ligase RAD18 (RAD18) antibodyRAD18 Reaktivität: Human, Ratte, Maus IF Wirt: Kaninchen Polyclonal unconjugated
anti-E3 ubiquitin-protein ligase RAD18 (RAD18) (AA 1-495) antibodyRAD18 Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-E3 ubiquitin-protein ligase RAD18 (RAD18) (Center) antibodyRAD18 Reaktivität: Human IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-E3 ubiquitin-protein ligase RAD18 (RAD18) (Internal Region) antibodyRAD18 Reaktivität: Human, Ratte WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
-
- Applikationshinweise
-
1) Western blotting: 1,000 fold dilution
2) Indirect immunofluorescence staining
3) Immunoprecipitation - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS, 50 % glycerol
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C
-
-
: "Rad18 guides poleta to replication stalling sites through physical interaction and PCNA monoubiquitination." in: The EMBO journal, Vol. 23, Issue 19, pp. 3886-96, (2004) (PubMed).
: "Differential regulation of Rad18 through Rad6-dependent mono- and polyubiquitination." in: The Journal of biological chemistry, Vol. 280, Issue 1, pp. 515-24, (2004) (PubMed).
: "Dysfunction of human Rad18 results in defective postreplication repair and hypersensitivity to multiple mutagens." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 14, pp. 7927-32, (2000) (PubMed).
-
: "Rad18 guides poleta to replication stalling sites through physical interaction and PCNA monoubiquitination." in: The EMBO journal, Vol. 23, Issue 19, pp. 3886-96, (2004) (PubMed).
-
- Target
- RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))
- Andere Bezeichnung
- Rad18 (RAD18 Produkte)
- Hintergrund
- The Rad6-Rad18 pair of genes plays a critical role in post-replication repair of damaged DNA. Rad6 protein functions as an E2 enzyme and Rad18 (495 aa, 56 kDa) as an ubiquitine ligase (E3) which ubiquitinates PCNA. Rad18 recruits translesion DNA polymerases to damaged DNA.
-
