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Shugoshin Antikörper

SGOL1 Reaktivität: Schizosaccharomyces pombe WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2452123
  • Target Alle Shugoshin (SGOL1) Antikörper anzeigen
    Shugoshin (SGOL1) (Shugoshin 1 (SGOL1))
    Reaktivität
    • 45
    • 5
    • 5
    • 1
    Schizosaccharomyces pombe
    Wirt
    • 42
    • 3
    Kaninchen
    Klonalität
    • 43
    • 2
    Polyklonal
    Konjugat
    • 24
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Shugoshin Antikörper ist unkonjugiert
    Applikation
    • 30
    • 27
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Aufreinigung
    Affinity purified
    Sterilität
    Sterile filtered
    Top Product
    Discover our top product SGOL1 Primärantikörper
  • Applikationshinweise
    1) Western blotting: 1,000 fold dilution
    2) Immunofluoresece staining: 100 fold dilution
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.2 mg/mL
    Buffer
    1 mg/mL BSA, PBS ( pH 7.2), 50 % glycerol
    Konservierungsmittel
    Azide free
    Lagerung
    -20 °C
  • Yamagishi, Sakuno, Shimura, Watanabe: "Heterochromatin links to centromeric protection by recruiting shugoshin." in: Nature, Vol. 455, Issue 7210, pp. 251-5, (2008) (PubMed).

    Watanabe, Kitajima: "Shugoshin protects cohesin complexes at centromeres." in: Philosophical transactions of the Royal Society of London. Series B, Biological sciences, Vol. 360, Issue 1455, pp. 515-21, discussion 521, (2005) (PubMed).

    Kitajima, Kawashima, Watanabe: "The conserved kinetochore protein shugoshin protects centromeric cohesion during meiosis." in: Nature, Vol. 427, Issue 6974, pp. 510-7, (2004) (PubMed).

  • Target
    Shugoshin (SGOL1) (Shugoshin 1 (SGOL1))
    Abstract
    SGOL1 Produkte
    Synonyme
    sgo1 antikoerper, NY-BR-85 antikoerper, SGO antikoerper, Sgo1 antikoerper, 3300001M08Rik antikoerper, C81037 antikoerper, shugoshin 1 antikoerper, shugoshin centromeric cohesion 1 antikoerper, shugoshin 1 L homeolog antikoerper, Sgo1 antikoerper, sgo1 antikoerper, sgo1.L antikoerper, SGO1 antikoerper
    Hintergrund
    Shugoshin 1 (Sgo1), a meiosis-specific protein, protects centromeric Rec8 from degradation during first meiotic division (meiosis I) in fission yeast Schizosaccharomyces pombe. This protein appears at late prophase of meiosis I and is degraded at anaphase I. Heterochromatin protein Swi6 associates directly with Sgo1. A point mutation of Sgo1 (V242E), which abolishes the interaction with Swi6, impairs the centromeric localization and function of Sgo1. The forced centromeric localization of Sgo1 restores proper meiotic chromosome segregation in swi6 cells. Using this antibody in Western blotting, the band of 37 kD was observed in wild type S. pombe MP111 extract.
    UniProt
    Q9P7A0
    Pathways
    Maintenance of Protein Location
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