A1CF Antikörper
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- Target Alle A1CF Antikörper anzeigen
- A1CF (APOBEC1 Complementation Factor (A1CF))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser A1CF Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- Antibody is purified by peptide affinity chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human A1CF.
- Top Product
- Discover our top product A1CF Primärantikörper
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- Applikationshinweise
- A1CF antibody can be used for detection of A1CF by ELISA at 1:1562500. A1CF antibody can be used for detection of A1CF by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Konzentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handhabung
- As with any antibody avoid repeat freeze-thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store A1CF antibody at -20 °C.
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- Target
- A1CF (APOBEC1 Complementation Factor (A1CF))
- Andere Bezeichnung
- A1CF (A1CF Produkte)
- Synonyme
- ACF antikoerper, ACF64 antikoerper, ACF65 antikoerper, APOBEC1CF antikoerper, ASP antikoerper, 1810073H04Rik antikoerper, Acf antikoerper, A1cft antikoerper, Apobec-1 antikoerper, acf antikoerper, acf64 antikoerper, acf65 antikoerper, apobec1cf antikoerper, asp antikoerper, A1CF antikoerper, APOBEC1 complementation factor antikoerper, apobec1 complementation factor antikoerper, APOBEC1 complementation factor L homeolog antikoerper, A1CF antikoerper, A1cf antikoerper, a1cf antikoerper, a1cf.L antikoerper
- Hintergrund
- Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. A1CF has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Alternative splicing occurs at this locus and three full-length transcript variants, encoding three distinct isoforms, have been described. Additional splicing has been observed but the full-length nature of these variants has not been determined.Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Alternative splicing occurs at this locus and three full-length transcript variants, encoding three distinct isoforms, have been described. Additional splicing has been observed but the full-length nature of these variants has not been determined.
- Molekulargewicht
- 65 kDa
- Gen-ID
- 29974
- NCBI Accession
- NP_620311
- UniProt
- Q9NQ94
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