MARCH2 Antikörper

Produktnummer ABIN2458695

Produktdetails anti-MARCH2 Antikörper

Target: MARCH2 (Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MARCH2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MARCH2.

Anwendungsinformationen

Applikationshinweise: MARCH2 antibody can be used for detection of 40239 by ELISA at 1:312500. MARCH2 antibody can be used for detection of 40239 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MARCH2 antibody at -20 °C.

Details zu MARCH2

Target: MARCH2 (Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2))

Andere Bezeichnung: MARCH2 (MARCH2 Produkte)

Synonyme: MARCH-II antikoerper, RNF172 antikoerper, rgd1306395 antikoerper, marh2 antikoerper, RGD1306395 antikoerper, 9530046H09Rik antikoerper, membrane associated ring-CH-type finger 2 antikoerper, membrane associated ring-CH-type finger 2 S homeolog antikoerper, E3 ubiquitin-protein ligase MARCH2 antikoerper, membrane-associated ring finger (C3HC4) 2 antikoerper, MARCH2 antikoerper, march2.S antikoerper, march2 antikoerper, Tsp_09446 antikoerper, marh2 antikoerper, March2 antikoerper

Hintergrund: MARCH2 is an E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC and CD86, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. MARCH2 may be involved in endosomal trafficking through interaction with STX6.

Molekulargewicht: 27 kDa

Gen-ID: 51257

NCBI Accession: NP_001005415

UniProt: Q9P0N8