RNF6
Reaktivität: Human
WB, ELISA
Wirt: Maus
Monoclonal
6D5
unconjugated
Applikationshinweise
RNF6 antibody can be used for detection of RNF6 by ELISA at 1:62500. RNF6 antibody can be used for detection of RNF6 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Konzentration
1 mg/mL
Buffer
Antibody is lyophilized in PBS buffer with 2 % sucrose.
Handhabung
As with any antibody avoid repeat freeze-thaw cycles.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
For short periods of storage (days) store at 4 °C. For longer periods of storage, store RNF6 antibody at -20 °C.
1200013I08Rik antikoerper, 5730419H05Rik antikoerper, AA537053 antikoerper, ring finger protein 6 antikoerper, ring finger protein (C3H2C3 type) 6 antikoerper, RNF6 antikoerper, Rnf6 antikoerper
Hintergrund
RNF6 contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed.