RNF139 Antikörper
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- Target Alle RNF139 Antikörper anzeigen
- RNF139 (Ring Finger Protein 139 (RNF139))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RNF139 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- Antibody is purified by peptide affinity chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RNF139.
- Top Product
- Discover our top product RNF139 Primärantikörper
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- Applikationshinweise
- RNF139 antibody can be used for detection of RNF139 by ELISA at 1:312500. RNF139 antibody can be used for detection of RNF139 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Konzentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handhabung
- As with any antibody avoid repeat freeze-thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store RNF139 antibody at -20 °C.
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- Target
- RNF139 (Ring Finger Protein 139 (RNF139))
- Andere Bezeichnung
- RNF139 (RNF139 Produkte)
- Synonyme
- HRCA1 antikoerper, RCA1 antikoerper, TRC8 antikoerper, 4930555P18Rik antikoerper, zgc:175173 antikoerper, rnf139 antikoerper, ring finger protein 139 antikoerper, ring finger protein 139 S homeolog antikoerper, RNF139 antikoerper, Rnf139 antikoerper, rnf139 antikoerper, rnf139.S antikoerper
- Hintergrund
- RNF139 is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t (3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP. The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t (3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.
- Molekulargewicht
- 76 kDa
- Gen-ID
- 11236
- NCBI Accession
- NP_009149
- UniProt
- Q8WU17
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