NSUN2 Antikörper
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- Target Alle NSUN2 Antikörper anzeigen
- NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NSUN2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- Antibody is purified by peptide affinity chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NSUN2.
- Top Product
- Discover our top product NSUN2 Primärantikörper
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- Applikationshinweise
- NSUN2 antibody can be used for detection of NSUN2 by ELISA at 1:62500. NSUN2 antibody can be used for detection of NSUN2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Konzentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handhabung
- As with any antibody avoid repeat freeze-thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store NSUN2 antibody at -20 °C.
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- Target
- NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))
- Andere Bezeichnung
- NSUN2 (NSUN2 Produkte)
- Synonyme
- D13Wsu123e antikoerper, Misu antikoerper, MISU antikoerper, MRT5 antikoerper, SAKI antikoerper, TRM4 antikoerper, RGD1311954 antikoerper, NOL1/NOP2/Sun domain family member 2 antikoerper, NOP2/Sun RNA methyltransferase family member 2 antikoerper, NOP2/Sun RNA methyltransferase family, member 2 antikoerper, NOP2/Sun RNA methyltransferase family member 2 S homeolog antikoerper, Nsun2 antikoerper, NSUN2 antikoerper, nsun2.S antikoerper
- Hintergrund
- Maturation of cytoplasmic tRNAs includes splicing of introns, which are located 1 nucleotide 3-prime from the anticodon in all intron-containing tRNA genes. In tRNA-leu (CAA), the first position of the anticodon, C34, is converted to 5-methylcytosine, a modification necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. NSUN2 is a methyltransferase that catalyzes the intron-dependent formation of 5-methylcytosine at C34 of tRNA-leu (CAA).Maturation of cytoplasmic tRNAs includes splicing of introns, which are located 1 nucleotide 3-prime from the anticodon in all intron-containing tRNA genes. In tRNA-leu (CAA), the first position of the anticodon, C34, is converted to 5-methylcytosine, a modification necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. NSUN2 encodes a methyltransferase that catalyzes the intron-dependent formation of 5-methylcytosine at C34 of tRNA-leu (CAA) (Brzezicha et al., 2006 [PubMed 17071714]).
- Molekulargewicht
- 86 kDa
- Gen-ID
- 54888
- NCBI Accession
- NP_060225
- UniProt
- Q08J23
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