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Protocadherin gamma Subfamily A, 4 (PCDHGA4) Antikörper

PCDHGA4 Reaktivität: Human, Maus, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2459280
  • Target Alle Protocadherin gamma Subfamily A, 4 (PCDHGA4) Antikörper anzeigen
    Protocadherin gamma Subfamily A, 4 (PCDHGA4)
    Reaktivität
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 3
    • 1
    Kaninchen
    Klonalität
    • 4
    Polyklonal
    Konjugat
    • 4
    Unkonjugiert
    Applikation
    Western Blotting (WB), ELISA
    Aufreinigung
    Antibody is purified by peptide affinity chromatography method.
    Immunogen
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PCDHGA4.
    Top Product
    Discover our top product PCDHGA4 Primärantikörper
  • Applikationshinweise
    PCDHGA4 antibody can be used for detection of PCDHGA4 by ELISA at 1:62500. PCDHGA4 antibody can be used for detection of PCDHGA4 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    Konzentration
    1 mg/mL
    Buffer
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    Handhabung
    As with any antibody avoid repeat freeze-thaw cycles.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store PCDHGA4 antibody at -20 °C.
  • Target
    Protocadherin gamma Subfamily A, 4 (PCDHGA4)
    Andere Bezeichnung
    PCDHGA4 (PCDHGA4 Produkte)
    Synonyme
    PCDH-GAMMA-A4 antikoerper, Pcdhga3 antikoerper, protocadherin gamma subfamily A, 4 antikoerper, PCDHGA4 antikoerper, Pcdhga4 antikoerper
    Hintergrund
    PCDHGA4 is a single-pass type I membrane protein. It contains 6 cadherin domains. PCDHGA4 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
    Molekulargewicht
    86 kDa
    Gen-ID
    56111
    NCBI Accession
    NP_114442
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