SPOP-B Antikörper
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- Target Alle SPOP-B Antikörper anzeigen
- SPOP-B (Speckle-Type POZ Protein (SPOP-B))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SPOP-B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- Antibody is purified by peptide affinity chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SPOP.
- Top Product
- Discover our top product SPOP-B Primärantikörper
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- Applikationshinweise
- SPOP antibody can be used for detection of SPOP by ELISA at 1:1562500. SPOP antibody can be used for detection of SPOP by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Konzentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handhabung
- As with any antibody avoid repeat freeze-thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store SPOP antibody at -20 °C.
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- Target
- SPOP-B (Speckle-Type POZ Protein (SPOP-B))
- Andere Bezeichnung
- SPOP (SPOP-B Produkte)
- Synonyme
- BTBD32 antikoerper, TEF2 antikoerper, AI315626 antikoerper, Pcif1 antikoerper, zgc:64140 antikoerper, spop antikoerper, tef2 antikoerper, speckle type BTB/POZ protein antikoerper, speckle-type POZ protein antikoerper, speckle type POZ protein S homeolog antikoerper, SPOP antikoerper, Spop antikoerper, spop antikoerper, spop.S antikoerper
- Hintergrund
- SPOP may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein.
- Molekulargewicht
- 42 kDa
- Gen-ID
- 8405
- NCBI Accession
- NP_001007227
- UniProt
- O43791
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