FUCA1 Antikörper

Produktnummer ABIN2459727

Produktdetails anti-FUCA1 Antikörper

Target: FUCA1 (Fucosidase, alpha-L- 1, Tissue (FUCA1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FUCA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FUCA1.

Anwendungsinformationen

Applikationshinweise: FUCA1 antibody can be used for detection of FUCA1 by ELISA at 1:312500. FUCA1 antibody can be used for detection of FUCA1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store FUCA1 antibody at -20 °C.

Details zu FUCA1

Target: FUCA1 (Fucosidase, alpha-L- 1, Tissue (FUCA1))

Andere Bezeichnung: FUCA1 (FUCA1 Produkte)

Synonyme: FUCA antikoerper, FUCA1 antikoerper, 0610006A03Rik antikoerper, 9530055J05Rik antikoerper, Afuc antikoerper, Fuca antikoerper, fuca antikoerper, fuca1 antikoerper, ATFUC1 antikoerper, F24D13.11 antikoerper, F24D13_11 antikoerper, alpha-L-fucosidase 1 antikoerper, wu:fb02a09 antikoerper, zgc:101116 antikoerper, alpha-L-fucosidase 1 antikoerper, fucosidase, alpha-L- 1, tissue antikoerper, alpha-L-fucosidase 1 L homeolog antikoerper, alpha-L-fucosidase 1, tandem duplicate 2 antikoerper, FUCA1 antikoerper, Fuca1 antikoerper, fuca1.L antikoerper, fuca1 antikoerper, FUC1 antikoerper, LOC9317020 antikoerper, LOC100285202 antikoerper, fuca1.2 antikoerper

Hintergrund: Alpha-L-fucosidase (EC 3.2.1.51) is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids. At least 2 separate polymorphic alpha-L-fucosidases are recognized in man: that in tissues, FUCA1, which is deficient in fucosidosis, and that in plasma, FUCA2. Fucosidosis is an autosomal recessive lysosomal storage disease caused by defective alpha-L-fucosidase with accumulation of fucose in the tissues. Different phenotypes include clinical features such as neurologic deterioration, growth retardation, visceromegaly, and seizures in a severe early form, coarse facial features, angiokeratoma corporis diffusum, spasticity and delayed psychomotor development in a longer surviving form, and an unusual spondylometaphyseoepiphyseal dysplasia in yet another form.

Molekulargewicht: 54 kDa

Gen-ID: 2517

NCBI Accession: NP_000138

UniProt: P04066

Pathways: Glycosaminoglycan Metabolic Process