SPO11
Reaktivität: Human
Wirt: Kaninchen
Polyclonal
FITC
Applikationshinweise
SPO11 antibody can be used for detection of SPO11 by ELISA at 1:1562500. SPO11 antibody can be used for detection of SPO11 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Konzentration
1 mg/mL
Buffer
Antibody is lyophilized in PBS buffer with 2 % sucrose.
Handhabung
As with any antibody avoid repeat freeze-thaw cycles.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
For short periods of storage (days) store at 4 °C. For longer periods of storage, store SPO11 antibody at -20 °C.
Target
SPO11
(SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11))
CT35 antikoerper, SPATA43 antikoerper, TOPVIA antikoerper, zgc:77876 antikoerper, AI449549 antikoerper, Meiotic recombination protein spo-11 antikoerper, SPO11, initiator of meiotic double stranded breaks antikoerper, SPO11 meiotic protein covalently bound to DSB antikoerper, spo-11 antikoerper, SPO11 antikoerper, Spo11 antikoerper, spo11 antikoerper
Hintergrund
Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs. SPO11 is similar in sequence and conserved features to the yeast meiotic recombination protein. It belongs to the TOP6A protein family. Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs. The protein encoded by this gene is similar in sequence and conserved features to the yeast meiotic recombination protein. The encoded protein belongs to the TOP6A protein family. Several transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been described.