SNW1 Antikörper

Produktnummer ABIN2460414

Produktdetails anti-SNW1 Antikörper

Target: SNW1 (SNW Domain Containing 1 (SNW1))

Reaktivität: Human, Hund, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNW1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SKIIP.

Anwendungsinformationen

Applikationshinweise: SKIIP antibody can be used for detection of SKIIP by ELISA at 1:62500. SKIIP antibody can be used for detection of SKIIP by western blot at 1.0-5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SKIIP antibody at -20 °C.

Details zu SNW1

Target: SNW1 (SNW Domain Containing 1 (SNW1))

Andere Bezeichnung: SKIIP (SNW1 Produkte)

Synonyme: Gle1l1 antikoerper, Skiip antikoerper, bx42 antikoerper, ncoa-62 antikoerper, prp45 antikoerper, prpf45 antikoerper, skiip antikoerper, skip antikoerper, Bx42 antikoerper, NCOA-62 antikoerper, PRPF45 antikoerper, Prp45 antikoerper, SKIIP antikoerper, SKIP antikoerper, 2310008B08Rik antikoerper, AW048543 antikoerper, NCoA-62 antikoerper, SNW domain containing 1 antikoerper, nuclear protein SkiP antikoerper, puff-specific protein Bx42 antikoerper, putative nuclear protein SkiP antikoerper, GLE1 RNA export mediator homolog (yeast), pseudogene 1 antikoerper, SNW domain containing 1 S homeolog antikoerper, snw1 antikoerper, PVX_002605 antikoerper, LOC5564605 antikoerper, Smp_105860 antikoerper, UREG_03916 antikoerper, Gle1-ps1 antikoerper, snw1.S antikoerper, SNW1 antikoerper, Snw1 antikoerper

Hintergrund: SKIIP (Nuclear Protein SkiP, nuclear receptor coactivator NCoA-62, ski-interacting protein) is a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also interact with poly (A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.

Molekulargewicht: 61 kDa

Gen-ID: 22938

NCBI Accession: NP_036377

UniProt: Q13573

Pathways: Retinoic Acid Receptor Signaling Pathway