NFIL3 Antikörper
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- Target Alle NFIL3 Antikörper anzeigen
- NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NFIL3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- Antibody is purified by protein A chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NFIL3.
- Top Product
- Discover our top product NFIL3 Primärantikörper
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- Applikationshinweise
- NFIL3 antibody can be used for detection of NFIL3 by ELISA at 1:312500. NFIL3 antibody can be used for detection of NFIL3 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Konzentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handhabung
- As with any antibody avoid repeat freeze-thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store NFIL3 antibody at -20 °C.
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- Target
- NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))
- Andere Bezeichnung
- NFIL3 (NFIL3 Produkte)
- Synonyme
- e4bp4 antikoerper, il3bp1 antikoerper, nfil3a antikoerper, nf-il3a antikoerper, MGC107826 antikoerper, NFIL3 antikoerper, E4BP4 antikoerper, IL3BP1 antikoerper, NF-IL3A antikoerper, NFIL3A antikoerper, E4BP4-1 antikoerper, zgc:100867 antikoerper, AV225605 antikoerper, nuclear factor, interleukin 3 regulated antikoerper, nuclear factor, interleukin 3 regulated L homeolog antikoerper, nuclear factor, interleukin 3, regulated antikoerper, nfil3 antikoerper, NFIL3 antikoerper, Nfil3 antikoerper, nfil3.L antikoerper
- Hintergrund
- NFIL3 is a basic leucine zipper (bZIP) transcription factor that represses or activates transcription in non-osteoblastic cells. NFIL3 play a role in attenuation of PTH target gene transcription in osteoblasts. NFIL3 repression domain interacts specifically with the TBP binding repressor protein Dr1.Glucocorticoid-mediated upregulation of the bZIP transcriptional repressor gene, NFIL3, is dependent on [Ca2+]i levels, and correlates with Glucocorticoid-evoked apoptosis of Glucocorticoid-sensitive CEM-C7-14 cells. NFIL3 is involved in a distinct growth factor-regulated signaling pathway that is responsible for the survival of early B-cell progenitors, and whose alteration by E2A-HLF leads to childhood B lineage leukemia.
- Molekulargewicht
- 51 kDa
- Gen-ID
- 4783
- NCBI Accession
- NP_005375
- UniProt
- Q14211
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