GADD45B
Reaktivität: Human
ELISA
Wirt: Kaninchen
Polyclonal
Biotin
Applikationshinweise
GADD45B antibody can be used for detection of GADD45B by ELISA at 1:1562500. GADD45B antibody can be used for detection of GADD45B by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Konzentration
1 mg/mL
Buffer
Antibody is lyophilized in PBS buffer with 2 % sucrose.
Handhabung
As with any antibody avoid repeat freeze-thaw cycles.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
For short periods of storage (days) store at 4 °C. For longer periods of storage, store GADD45B antibody at -20 °C.
Target
GADD45B
(Growth Arrest and DNA-Damage-Inducible, beta (GADD45B))
GADD45BETA antikoerper, MYD118 antikoerper, AI323528 antikoerper, Myd118 antikoerper, CS131 antikoerper, cb196 antikoerper, gadd45b antikoerper, gadd45b2 antikoerper, sb:cb196 antikoerper, zgc:73104 antikoerper, gadd45beta antikoerper, wu:fa92d10 antikoerper, wu:fa98h12 antikoerper, wu:fk65h03 antikoerper, zgc:111973 antikoerper, gadd45b1 antikoerper, gadd45bl antikoerper, zgc:112453 antikoerper, growth arrest and DNA damage inducible beta antikoerper, growth arrest and DNA-damage-inducible 45 beta antikoerper, growth arrest and DNA-damage-inducible, beta antikoerper, growth arrest and DNA-damage-inducible, beta a antikoerper, growth arrest and DNA-damage-inducible, beta b antikoerper, GADD45B antikoerper, Gadd45b antikoerper, gadd45ba antikoerper, gadd45bb antikoerper
Hintergrund
The function of GADD45B is involved in the regulation of growth and apoptosis.This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.