Coilin Antikörper

Produktnummer ABIN2463583

Produktdetails anti-Coilin Antikörper

Target: Coilin (COIL)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Coilin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human COIL.

Anwendungsinformationen

Applikationshinweise: COIL antibody can be used for detection of COIL by ELISA at 1:312500. COIL antibody can be used for detection of COIL by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store COIL antibody at -20 °C.

Details zu Coilin

Target: Coilin (COIL)

Andere Bezeichnung: COIL (COIL Produkte)

Synonyme: p80c antikoerper, coil antikoerper, CG8710 antikoerper, Coilin antikoerper, Dmel\\CG8710 antikoerper, LOC100218802 antikoerper, F3F19.5 antikoerper, F3F19_5 antikoerper, CLN80 antikoerper, p80-coilin antikoerper, C79982 antikoerper, Cln80 antikoerper, p80 antikoerper, wu:fb08h11 antikoerper, sph1 antikoerper, Coilin antikoerper, coilin antikoerper, sphere organelles protein-like protein antikoerper, coilin p80 antikoerper, coilin L homeolog antikoerper, p80c antikoerper, COIL antikoerper, coil antikoerper, AT1G13030 antikoerper, Coil antikoerper, coil.L antikoerper

Hintergrund: COIL is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies.The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molekulargewicht: 63 kDa

Gen-ID: 8161

NCBI Accession: NP_004636

UniProt: P38432

Pathways: Ribonucleoprotein Complex Subunit Organization