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MST1R Antikörper (Internal Region)
MST1R
Reaktivität: Human, Gibbon
ELISA, IHC
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN2469459
Produktdetails anti-MST1R Antikörper
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Target
Alle MST1R Antikörper anzeigen
MST1R
(Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R))
Bindungsspezifität
Alle Epitope für MST1R Antikörper
Internal Region
Reaktivität
Alle Reaktivitäten für MST1R Antikörper
Human, Gibbon
Wirt
Alle Wirte für MST1R Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für MST1R Antikörper
Polyklonal
Konjugat
Alle Konjugate für MST1R Antikörper
Dieser MST1R Antikörper ist unkonjugiert
Applikation
Alle Applikationen für MST1R Antikörper
ELISA, Immunohistochemistry (IHC)
Spezifität
BLAST analysis of the peptide immunogen showed no homology with other human proteins, except FANCE (50 % ).
Aufreinigung
Immunoaffinity Chromatography
Immunogen
MST1R antibody was raised against a peptide located near the internal domain of MST1R (Human).
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Discover our top product MST1R Primärantikörper
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Anwendungsinformationen
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Applikationshinweise
MST1R antibody can be used in immunohistochemistry starting at 20 μg/mL.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
PBS, 0.1 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
As with all antibodies avoid freeze/thaw cycles.
Lagerung
4 °C/-80 °C
Informationen zur Lagerung
MST1R antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.
Details zu MST1R
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Target
MST1R
(Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R))
Andere Bezeichnung
MST1R (MST1R Produkte )
Synonyme
CD136 antikoerper, CDw136 antikoerper, PTK8 antikoerper, RON antikoerper, Fv-2 antikoerper, Fv2 antikoerper, Ron antikoerper, STK antikoerper, Cdw136 antikoerper, Ptk8 antikoerper, Stk antikoerper, macrophage stimulating 1 receptor antikoerper, macrophage stimulating 1 receptor (c-met-related tyrosine kinase) antikoerper, MST1R antikoerper, Mst1r antikoerper
Hintergrund
MST1R/Ron, a HGF Receptor/MET-type protein kinase, mediates the biological activities of macrophage-stimulating protein (MSP), a multifunctional cytokine that regulates cell adhesion, motility, growth, and survival. The protein is a membrane-spanning, disulfide-linked heterodimer, which results from cleavage of a glycosylated precursor into 35-kD (alpha) and 150-kD (beta) subunits. Ligand binding results in tyrosine phosphorylation of the beta chain. In knockout studies, MST1R/RON (-/-) mice failed to survive past the periimplantation period. The MST1R/RON gene has been mapped to 3p21, a region of frequent deletion or mutation in small cell lung and renal carcinoma, and has been implicated in the progression of several epithelial cancers.
Gen-ID
4486
UniProt
Q04912
Pathways
RTK Signalweg
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