PDE1C Antikörper (C-Term)

Produktnummer ABIN2469467

Produktdetails anti-PDE1C Antikörper

Target: PDE1C (phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Fledermaus, Hamster, Affe, Gibbon, Gorilla, Orang-Utan

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE1C Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Spezifität: BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Aufreinigung: Immunoaffinity Chromatography

Immunogen: PDE1C antibody was raised against a peptide located in the C-Terminal domain of PDE1C (Human).

Anwendungsinformationen

Applikationshinweise: PDE1C antibody can be used in immunohistochemistry starting at 10 μg/mL, and flow cytometry.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies avoid freeze/thaw cycles.

Lagerung: 4 °C/-80 °C

Informationen zur Lagerung: PDE1C antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Details zu PDE1C

Target: PDE1C (phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C))

Andere Bezeichnung: PDE1C (PDE1C Produkte)

Synonyme: CG14940 antikoerper, CG14942 antikoerper, CG14943 antikoerper, CG14944 antikoerper, CG31757 antikoerper, CG31758 antikoerper, CG42325 antikoerper, CG44007 antikoerper, Dmel\\CG44007 antikoerper, Dmel_CG14940 antikoerper, Dmel_CG14943 antikoerper, Dmel_CG14944 antikoerper, Dmel_CG31757 antikoerper, Dmel_CG31758 antikoerper, Dmel_CG42325 antikoerper, PDE1C antikoerper, PDE1c antikoerper, GB13690 antikoerper, Hcam3 antikoerper, Phosphodiesterase 1c antikoerper, phosphodiesterase 1C antikoerper, calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A antikoerper, calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C antikoerper, phosphodiesterase 1C, calmodulin-dependent b antikoerper, Pde1c antikoerper, PDE1C antikoerper, LOC724389 antikoerper, LOC100019026 antikoerper, pde1cb antikoerper

Hintergrund: Phosphodiesterase 1C is a cAMP/cGMP dual-specific, calcium/calmodullin-dependent phosphodiesterase. PDE1C has been shown to affect vascular smooth muscle proliferation and atherosclerosis, insulin secretion regulation, spermatozoa development, and erectile dysfunction. At least five PDE1C isoforms have been reported, the expression of which are regulated in a tissue/cell-specific manner.

Gen-ID: 5137

UniProt: Q14123

Pathways: EGFR Signaling Pathway, Neurotrophin Signalübertragung, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma