TLX1 Antikörper (AA 300-330)
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- Target Alle TLX1 Antikörper anzeigen
- TLX1 (T-Cell Leukemia Homeobox 1 (TLX1))
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Bindungsspezifität
- AA 300-330
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Reaktivität
- Maus, Human, Ratte, Rind (Kuh), Hund, Kaninchen, Fledermaus, Affe, Huhn, Pferd, Hamster, Gibbon, Gorilla
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TLX1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Aufreinigung
- Protein G Column
- Immunogen
- TLX1 antibody was raised against amino acids 300 - 330 of TLX1 (Human).
- Isotyp
- IgG
- Top Product
- Discover our top product TLX1 Primärantikörper
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- Applikationshinweise
- TLX1 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS, 0.2 % gelatin, 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- As with all antibodies avoid freeze/thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- TLX1 antibody can be stored short term 4 °C. For long term storage aliquot and store at -20 °C.
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- Target
- TLX1 (T-Cell Leukemia Homeobox 1 (TLX1))
- Andere Bezeichnung
- TLX1 (TLX1 Produkte)
- Synonyme
- Hox-11 antikoerper, Hox11 antikoerper, HOX11 antikoerper, TCL3 antikoerper, XHox11 antikoerper, XHox11L2 antikoerper, hox11 antikoerper, tlx1-a antikoerper, TLX-1 antikoerper, RGD1563655 antikoerper, SI:dZ46P4.1 antikoerper, Tlx-1 antikoerper, ztlx-1 antikoerper, T cell leukemia, homeobox 1 antikoerper, T-cell leukemia homeobox 1 antikoerper, T-cell leukemia homeobox 1 L homeolog antikoerper, T-cell leukemia, homeobox 1 antikoerper, Tlx1 antikoerper, TLX1 antikoerper, tlx1.L antikoerper, tlx1 antikoerper
- Hintergrund
- HOX11, also called homeobox11 or Tcl-3 is located at the 10q24 T-Cell translocation breakpoint region. It encodes a homeobox-domain containing protein, HOX11, containing a glycine and proline-rich amino terminus. HOX11 is required for maintenance of the developing spleen and cell survival. The HOX11protein binds to a specific DNA sequence and localizes to the cell nucleus. It transactivates transcription of a reporter gene linked to a cis-regulatory element, acting as a positive transcription activator. The HOX11 gene is highly expressed in T-ALLs as a result of a t (7:10) (q35,q24) or t(10:14)(q24,qll) translocation. The homeobox gene is deregulated upon translocation into the T-cell receptor locus and activates a specific subset of tumor-associated target genes. HOX 11 gene translocation has been attributed to T-cell leukemia and lymphoid neoplasias.
- Gen-ID
- 3195
- UniProt
- P31314
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