Endothelin Antikörper (C-Term)

Produktnummer ABIN2473437

Produktdetails anti-Endothelin Antikörper

Target: Endothelin

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Endothelin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoradiometric Assay (IRMA)

Spezifität: Reacts with the C terminal of endothelins 1, 2 and 3. 3G10 does not react with the endothelin precursor molecule, big endothelin. The endothelins are potent vasoconstrictors and critical components in the progression of pulmonary arterial hypertension a devastating and rapidly progressive condition that leads to right ventricular strain and dysfunction.

Produktmerkmale: Purified IgG

Aufreinigung: Purified

Immunogen: Synthetic peptide corresponding to the c-terminal region of human endothelin (C,H,L,D,I,I,W), conjugated to BSA.

Klon: 3G10

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Referenzen für anti-Endothelin Antikörper (ABIN2473437)

Yao, Morioka, Li, Oite: "Endothelin is a potent inhibitor of matrix metalloproteinase-2 secretion and activation in rat mesangial cells." in: American journal of physiology. Renal physiology, Vol. 280, Issue 4, pp. F628-35, (2001) (PubMed).

Details zu Endothelin

Target: Endothelin

Abstract: Endothelin Produkte

Gen-ID: 1906, 1907, 1908

UniProt: P05305, P14138, P20800