HAVCR1 Antikörper (PE)

Produktnummer ABIN2476813

Produktdetails anti-HAVCR1 Antikörper (PE)

Target: HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser HAVCR1 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Produktmerkmale: Purified IgG conjugated to R. Phycoerythrin (RPE)

Immunogen: Full-length mouse Tim-1-Ig, containing both the IgV and mucin domains of Tim-1.

Klon: RMT1-10

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Referenzen für anti-HAVCR1 Antikörper (PE) (ABIN2476813)

Freeman, Casasnovas, Umetsu, DeKruyff: "TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity." in: Immunological reviews, Vol. 235, Issue 1, pp. 172-89, (2010) (PubMed).

Yuan, Ansari, DAddio, Paez-Cortez, Schmitt, Donnarumma, Boenisch, Zhao, Popoola, Clarkson, Yagita, Akiba, Freeman, Iacomini, Turka, Glimcher, Sayegh: "Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 26, pp. 10734-9, (2009) (PubMed).

Xiao, Najafian, Reddy, Albin, Zhu, Jensen, Imitola, Korn, Anderson, Zhang, Gutierrez, Moll, Sobel, Umetsu, Yagita, Akiba, Strom, Sayegh, DeKruyff, Khoury, Kuchroo: "Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function." in: The Journal of experimental medicine, Vol. 204, Issue 7, pp. 1691-702, (2007) (PubMed).

Details zu HAVCR1

Target: HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))

Andere Bezeichnung: TIM-1 (HAVCR1 Produkte)

Substanzklasse: Virus

Hintergrund: Synonyms: T-CELL IMMUNOGLOBULIN MUCIN 1

Gen-ID: 171283

UniProt: Q5QNS5