DUX4 Antikörper (C-Term) (Atto 390)
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- Target Alle DUX4 Antikörper anzeigen
- DUX4 (Double Homeobox 4 (DUX4))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser DUX4 Antikörper ist konjugiert mit Atto 390
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- Detects ~45 kDa. No cross-reactivity with DUX4c.
- Kreuzreaktivität
- Human, Maus
- Aufreinigung
- Protein G Purified
- Immunogen
- C-terminal 76 amino acids of DUX4 with glutathione-s-transferase (gst) tag
- Klon
- P2B1
- Isotyp
- IgG1
- Top Product
- Discover our top product DUX4 Primärantikörper
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- Applikationshinweise
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- WB (1:1000)
- ICC/IF (1:1000)
- optimal dilutions for assays should be determined by the user.
- Kommentare
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1 μg/ml of ABIN2482286 was sufficient for detection of DUX4 in 20 μg of HeLa cell lysate by ECL immunoblot analysis using goat anti-mouse IgG: HRP as teh secondary.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Conjugated antibodies should be stored at 4°C
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- Target
- DUX4 (Double Homeobox 4 (DUX4))
- Andere Bezeichnung
- DUX4 (DUX4 Produkte)
- Synonyme
- DUX4 antikoerper, DUX4L antikoerper, double homeobox, 4 antikoerper, double homeobox 4 antikoerper, DUX4 antikoerper
- Hintergrund
- DUX4, or double homeobox4, is a human protein that is a transcriptional activator of paired-like homeodomain transcription factor 1 (1). Clinically it is a facioscapulohumeral muscular dystrophy candidate gene that appears to have a toxic gain of function (2-4). In FSHD individuals, the expression of the full-length DUX4 transcript is not completely suppressed in skeletal muscle and possibly other differentiated tissues (5).
- Gen-ID
- 22947
- NCBI Accession
- NP_149418
- UniProt
- F5GZ66
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