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Piccolo Antikörper (PE)

Dieses Anti-Piccolo-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Piccolo in WB und IHC. Geeignet für Human.
Produktnummer ABIN2482403

Kurzübersicht für Piccolo Antikörper (PE) (ABIN2482403)

Target

Piccolo (PIC)

Reaktivität

  • 22
  • 16
  • 7
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 18
  • 14
  • 1
  • 1
Kaninchen

Klonalität

  • 20
  • 14
Polyklonal

Konjugat

  • 14
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Dieser Piccolo Antikörper ist konjugiert mit PE

Applikation

  • 29
  • 16
  • 15
  • 12
  • 10
  • 2
Western Blotting (WB), Immunohistochemistry (IHC)
  • Spezifität

    Detects ~550 kDa. No cross-reactivity to Bassoon.

    Kreuzreaktivität

    Human, Maus, Ratte

    Aufreinigung

    Protein A Purified

    Immunogen

    Recombinant Full length Protein, BC001304.1
  • Applikationshinweise

    • WB (1:1000)
    • IHC (1:400)
    • optimal dilutions for assays should be determined by the user.

    Kommentare

    1 μg/ml of ABIN2482403 was sufficient for detection of Piccolo in 10 μg of rat brain tissue lysate by colorimetric immunoblot analysis using goat ant rabbit IgG:HRP as the secondary antibody.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Conjugated antibodies should be stored at 4°C
  • Target

    Piccolo (PIC)

    Andere Bezeichnung

    Piccolo

    Hintergrund

    Piccolo, also referred to as Aczonin, is a large protein which consists of an N-terminal Zn2+ finger, several piccolo-bassoon homology domains and C-terminal PDZ and C2 domains (1, 2). In general it is found together with bassoon, a related huge multi-domain protein of the CAZ (cytoskeletal matric assembled at active zones) (3). Piccolo is a scaffolding protein for proteins involved in endo- and exocytosis of synaptic vesicles. Piccolo has also been shown to interfere with clathrin medicated endocytosis by binding to the F-actin and dynamin binding protein Abp1 (2).

    Gen-ID

    27445

    NCBI Accession

    NP_055325

    UniProt

    Q9Y6V0
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