DICER1 Antikörper (AA 1638-1899) (APC)
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- Target Alle DICER1 Antikörper anzeigen
- DICER1 (Dicer 1, Ribonuclease Type III (DICER1))
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Bindungsspezifität
- AA 1638-1899
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Reaktivität
- Maus
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser DICER1 Antikörper ist konjugiert mit APC
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Applikation
- Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Spezifität
- Detects ~215 kDa.
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Protein G Purified
- Immunogen
- Fusion protein amino acids 1638-1899 of mouse Endoribonuclease Dicer
- Klon
- S167-7
- Isotyp
- IgG1
- Top Product
- Discover our top product DICER1 Primärantikörper
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- Applikationshinweise
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- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- Kommentare
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1 μg/ml of ABIN2483011 was sufficient for detection of Dicer in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Conjugated antibodies should be stored at 4°C
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- Target
- DICER1 (Dicer 1, Ribonuclease Type III (DICER1))
- Andere Bezeichnung
- Dicer (DICER1 Produkte)
- Synonyme
- dcr1 antikoerper, dicer antikoerper, herna antikoerper, DICER1 antikoerper, dicer1 antikoerper, 1110006F08Rik antikoerper, D12Ertd7e antikoerper, mKIAA0928 antikoerper, DCR1 antikoerper, Dicer antikoerper, HERNA antikoerper, MNG1 antikoerper, DICER antikoerper, fc39d11 antikoerper, fc74b05 antikoerper, wu:fc39d11 antikoerper, wu:fc74b05 antikoerper, dicer 1, ribonuclease III antikoerper, endoribonuclease Dicer antikoerper, dicer 1, ribonuclease III S homeolog antikoerper, dicer 1, ribonuclease type III antikoerper, dicer 1 ribonuclease III antikoerper, DICER1 antikoerper, CpipJ_CPIJ010534 antikoerper, dicer1 antikoerper, dicer1.S antikoerper, Dicer1 antikoerper
- Hintergrund
- Dicer is a member of the RNase III family that specifically cleaves double-stranded RNAs to generate microRNAs (miRNAs) (1). After long primary transcript pri-miRNAs are processed to stem-looped pre-miRNAs by Drosha (2), pre-miRNAs are transported to the cytoplasm and further processed by Dicer to produce 22-nucleotide mature miRNAs (3). The mature miRNA then becomes a part of the RNA-Induced Silencing Complex (RISC) and can bind to the 3' UTR of the target mRNA (3)
- Gen-ID
- 192119
- NCBI Accession
- NP_683750
- UniProt
- Q8R418
- Pathways
- Regulatorische RNA Pathways, Stem Cell Maintenance, Ribonucleoprotein Complex Subunit Organization
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