SLC17A7 Antikörper (AA 493-560) (Atto 488)
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- Target Alle SLC17A7 Antikörper anzeigen
- SLC17A7 (Solute Carrier Family 17 (Vesicular Glutamate Transporter), Member 7 (SLC17A7))
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Bindungsspezifität
- AA 493-560
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Reaktivität
- Ratte
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser SLC17A7 Antikörper ist konjugiert mit Atto 488
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Spezifität
- Detects ~52 kDa. No cross-reactivity against VGlut2.
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Protein G Purified
- Immunogen
- Fusion protein amino acids 493-560 (cytoplasmic C-terminus) of rat VGlut1
- Klon
- S28-9
- Isotyp
- IgG1
- Top Product
- Discover our top product SLC17A7 Primärantikörper
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- Applikationshinweise
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- WB (1:1000)
- optimal dilutions for assays should be determined by the user.
- Kommentare
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1 μg/ml of ABIN2483717 was sufficient for detection of VGLut1 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Conjugated antibodies should be stored at 4°C
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- Target
- SLC17A7 (Solute Carrier Family 17 (Vesicular Glutamate Transporter), Member 7 (SLC17A7))
- Andere Bezeichnung
- VGLUT1 (SLC17A7 Produkte)
- Synonyme
- 2900052E22Rik antikoerper, AI851913 antikoerper, VGluT1 antikoerper, Vglut1 antikoerper, BNPI antikoerper, VGLUT1 antikoerper, slc17a7 antikoerper, vglut1 antikoerper, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 antikoerper, solute carrier family 17 member 7 antikoerper, solute carrier family 17 (vesicular glutamate transporter), member 7a antikoerper, Slc17a7 antikoerper, SLC17A7 antikoerper, slc17a7a antikoerper
- Hintergrund
- VGLUT1 is expressed in a subset of glutamate neurons and transports glutamate into native synaptic vesicles from the brain, exhibiting a conductance for chloride that is blocked by glutamate (1). Vesicular glutamate transport has a substantially lower apparent affinity than the plasma membrane excitatory amino acid transporters. Glutamate transport by VGLUT1 is saturated with a K(m) of approximately 2 mM, in the same range as transport by synaptic vesicles. Finally, plasma membrane glutamate transporters recognize both aspartate and glutamate as substrates, whereas VGLUT1 does not recognize aspartate (2).
- Gen-ID
- 116638
- NCBI Accession
- NP_446311
- UniProt
- Q62634
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