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AMIGO1 Antikörper (AA 554-574) (Atto 390)

AMIGO1 Reaktivität: Human WB, IHC, ICC, IF Wirt: Maus Monoclonal S86-36 Atto 390
Produktnummer ABIN2483801
  • Target Alle AMIGO1 Antikörper anzeigen
    AMIGO1 (Adhesion Molecule with Ig-Like Domain 1 (AMIGO1))
    Bindungsspezifität
    • 15
    • 12
    • 9
    • 8
    • 5
    • 5
    • 1
    AA 554-574
    Reaktivität
    • 39
    • 22
    • 7
    • 3
    • 3
    • 3
    Human
    Wirt
    • 40
    • 14
    Maus
    Klonalität
    • 40
    • 14
    Monoklonal
    Konjugat
    • 13
    • 6
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser AMIGO1 Antikörper ist konjugiert mit Atto 390
    Applikation
    • 49
    • 19
    • 16
    • 14
    • 13
    • 13
    • 11
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Spezifität
    Detects ~60-80 kDa depending on maturity/glycosylation.
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Protein G Purified
    Immunogen
    Fusion protein amino acids 554-574 (cytoplasmic C-terminus) of human AMIGO-1
    Klon
    S86-36
    Isotyp
    IgG1
    Top Product
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  • Applikationshinweise
    • WB (1:1000)
    • optimal dilutions for assays should be determined by the user.
    Kommentare

    1 μg/ml of ABIN2483801 was sufficient for detection of AMIGO-1 in 20 μg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Conjugated antibodies should be stored at 4°C
  • Target
    AMIGO1 (Adhesion Molecule with Ig-Like Domain 1 (AMIGO1))
    Andere Bezeichnung
    AMIGO1 (AMIGO1 Produkte)
    Synonyme
    A antikoerper, Amigo antikoerper, ali2 antikoerper, AMIGO antikoerper, AMIGO-1 antikoerper, adhesion molecule with Ig like domain 1 antikoerper, Amigo1 antikoerper, AMIGO1 antikoerper
    Hintergrund
    The amphoterin-induced gene and ORF (AMIGO) family of proteins consists of AMIGO1, AMIGO2 and AMIGO3. All three members are single pass type I membrane proteins that contain several leucine-rich repeats, one IgG domain and a transmembrane domain. The AMIGO proteins are specifically expressed on fiber tracts of neuronal tissues and participate in their formation. They can form complexes with each other, but can also self-bind. AMIGO1, also designated Alivin2, promotes growth and fasciculation of neurites and plays a role in myelination and fasciculation of developing neural axons. In cerebellar neurons, AMIGO2 (Alivin1) is crucial for depolarization-dependent survival. Similar to AMIGO1 and AMIGO2, AMIGO3 (Alivin3) plays a role in hemophilic and/or heterophilic cell-cell interaction and signal transduction.
    Gen-ID
    57463
    NCBI Accession
    NP_065754
    UniProt
    Q86WK6
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