MDC1 Antikörper (N-Term) (Atto 488)
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- Target Alle MDC1 Antikörper anzeigen
- MDC1 (Mdc1 (MDC1))
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Bindungsspezifität
- N-Term
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Reaktivität
- Maus
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser MDC1 Antikörper ist konjugiert mit Atto 488
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- Detects ~184 kDa. This antibody recognizes MDC1 at and around the N-terminus.
- Kreuzreaktivität
- Schimpanse, Rind (Kuh), Human, Maus
- Aufreinigung
- Protein G Purified
- Immunogen
- GST-tagged recombinant protein corresponding to mouse MDC1 at and around the N-terminus
- Klon
- P2B11
- Isotyp
- IgG1
- Top Product
- Discover our top product MDC1 Primärantikörper
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- Applikationshinweise
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- WB (1:2000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- Kommentare
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0.5 μg/ml of ABIN2484142 was sufficient for detection of MDC1 in 10 μg of HeLa cell lysate by ECL immunoblot analysis.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Conjugated antibodies should be stored at 4°C
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- Target
- MDC1 (Mdc1 (MDC1))
- Andere Bezeichnung
- MDC1 (MDC1 Produkte)
- Synonyme
- 6820401C03 antikoerper, AA413496 antikoerper, Nfbd1 antikoerper, mKIAA0170 antikoerper, NFBD1 antikoerper, mediator of DNA damage checkpoint 1 antikoerper, mediator of DNA-damage checkpoint 1 antikoerper, Mdc1 antikoerper, MDC1 antikoerper
- Hintergrund
- MDC1, mediator of DNA damage checkpoint protein 1, plays a role in checkpoint mediated cell cycle arrest in response to DNA damage, within S phase and G2/M. It is also thought to act as a scaffold protein during recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage that are marked by phosphorylation of histone H2A.X on S139.
- Gen-ID
- 240087
- NCBI Accession
- NP_001010833
- UniProt
- Q5PSV9
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