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MDC1 Antikörper (N-Term) (Atto 488)

MDC1 Reaktivität: Maus WB, IF, ICC Wirt: Maus Monoclonal P2B11 Atto 488
Produktnummer ABIN2484142
  • Target Alle MDC1 Antikörper anzeigen
    MDC1 (Mdc1 (MDC1))
    Bindungsspezifität
    • 21
    • 17
    • 15
    • 10
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 60
    • 53
    • 16
    • 12
    • 11
    • 2
    • 1
    • 1
    Maus
    Wirt
    • 50
    • 36
    Maus
    Klonalität
    • 50
    • 36
    Monoklonal
    Konjugat
    • 30
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MDC1 Antikörper ist konjugiert mit Atto 488
    Applikation
    • 66
    • 30
    • 14
    • 13
    • 13
    • 12
    • 12
    • 10
    • 9
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    Detects ~184 kDa. This antibody recognizes MDC1 at and around the N-terminus.
    Kreuzreaktivität
    Schimpanse, Rind (Kuh), Human, Maus
    Aufreinigung
    Protein G Purified
    Immunogen
    GST-tagged recombinant protein corresponding to mouse MDC1 at and around the N-terminus
    Klon
    P2B11
    Isotyp
    IgG1
    Top Product
    Discover our top product MDC1 Primärantikörper
  • Applikationshinweise
    • WB (1:2000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    Kommentare

    0.5 μg/ml of ABIN2484142 was sufficient for detection of MDC1 in 10 μg of HeLa cell lysate by ECL immunoblot analysis.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Conjugated antibodies should be stored at 4°C
  • Target
    MDC1 (Mdc1 (MDC1))
    Andere Bezeichnung
    MDC1 (MDC1 Produkte)
    Synonyme
    6820401C03 antikoerper, AA413496 antikoerper, Nfbd1 antikoerper, mKIAA0170 antikoerper, NFBD1 antikoerper, mediator of DNA damage checkpoint 1 antikoerper, mediator of DNA-damage checkpoint 1 antikoerper, Mdc1 antikoerper, MDC1 antikoerper
    Hintergrund
    MDC1, mediator of DNA damage checkpoint protein 1, plays a role in checkpoint mediated cell cycle arrest in response to DNA damage, within S phase and G2/M. It is also thought to act as a scaffold protein during recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage that are marked by phosphorylation of histone H2A.X on S139.
    Gen-ID
    240087
    NCBI Accession
    NP_001010833
    UniProt
    Q5PSV9
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