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SERPINH1 Antikörper (APC)

SERPINH1 Reaktivität: Human WB, IF, ICC Wirt: Maus Monoclonal 1C4-1A6 APC
Produktnummer ABIN2484371
  • Target Alle SERPINH1 Antikörper anzeigen
    SERPINH1 (Serpin Family H Member 1 (SERPINH1))
    Reaktivität
    • 78
    • 37
    • 37
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 62
    • 27
    Maus
    Klonalität
    • 63
    • 26
    Monoklonal
    Konjugat
    • 40
    • 7
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SERPINH1 Antikörper ist konjugiert mit APC
    Applikation
    • 71
    • 31
    • 23
    • 21
    • 15
    • 8
    • 8
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    Detects 47 kDa.
    Kreuzreaktivität
    Human
    Aufreinigung
    Protein G Purified
    Immunogen
    Human HSP47, full length
    Klon
    1C4-1A6
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product SERPINH1 Primärantikörper
  • Applikationshinweise
    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    Kommentare

    1 μg/ml of ABIN2484371 was sufficient for detection of HSP47 in 20 μg of heat shocked HeLa cell lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Conjugated antibodies should be stored at 4°C
  • Target
    SERPINH1 (Serpin Family H Member 1 (SERPINH1))
    Andere Bezeichnung
    HSP47 (SERPINH1 Produkte)
    Synonyme
    AsTP3 antikoerper, CBP1 antikoerper, CBP2 antikoerper, HSP47 antikoerper, OI10 antikoerper, PPROM antikoerper, RA-A47 antikoerper, SERPINH2 antikoerper, gp46 antikoerper, SERPINH1 antikoerper, DKFZp468B197 antikoerper, cb216 antikoerper, hsp antikoerper, hsp47 antikoerper, id:ibd5060 antikoerper, wu:fc56b02 antikoerper, BERF-1 antikoerper, Cbp1 antikoerper, Cbp2 antikoerper, Hsp47 antikoerper, J6 antikoerper, Serpinh2 antikoerper, colligin antikoerper, astp3 antikoerper, cbp1 antikoerper, cbp2 antikoerper, pig14 antikoerper, pprom antikoerper, ra-a47 antikoerper, serpinh2 antikoerper, serpin family H member 1 antikoerper, serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b antikoerper, serpin H1 antikoerper, selenoprotein K antikoerper, serine (or cysteine) peptidase inhibitor, clade H, member 1 antikoerper, serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) L homeolog antikoerper, SERPINH1 antikoerper, serpinh1b antikoerper, LOC100009353 antikoerper, Selenok antikoerper, Serpinh1 antikoerper, serpinh1.L antikoerper
    Hintergrund
    HSP47 is a chaperone protein, member of the superfamily of serine proteinase inhibitors. Also known as SERPINH1, a serine proteinase inhibitor. It is a stress protein that resides in the endoplasmic reticulum, has an active role on the intracellular process of folding, assembly and secretion of pro-collagens. Recent studies have shown the association of on an increased expression of HSP47 around fibrotic lesions (1). The identification of a novel biomarker on cell therapies aimed to reduce the progression of fibrotic diseases, could be used potentially as a universal marker, since HSP47 binds a single substrate (2). Type I collagen is fundamental during the healing process after a myocardial infarction. It is critical in the position of collagen-produced cells and the assembly of collagen fibrils (3).
    Gen-ID
    871
    NCBI Accession
    NP_001193943
    UniProt
    P50454
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