CLCN3 Antikörper (AA 98-115) (Atto 390)

Produktnummer ABIN2485470

Produktdetails anti-CLCN3 Antikörper (Atto 390)

Target: CLCN3 (Chloride Channel 3 (CLCN3))

Bindungsspezifität: AA 98-115

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CLCN3 Antikörper ist konjugiert mit Atto 390

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Spezifität: Detects ~90 kDa. Does not cross-react with Clcn4 or Clcn5 (based on KO validation results).

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Protein G Purified

Immunogen: Synthetic peptide amino acids 98-115 (cytoplasmic N-terminus) of rat Clcn3

Klon: S258-5

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

• WB (1:1000)
• IHC (1:1000)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Kommentare:

1 μg/ml of ABIN2485470 was sufficient for detection of Clcn3 in 20 μg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Conjugated antibodies should be stored at 4°C

Details zu CLCN3

Target: CLCN3 (Chloride Channel 3 (CLCN3))

Andere Bezeichnung: ClCN3 (CLCN3 Produkte)

Synonyme: CLC3 antikoerper, ClC-3 antikoerper, Clc3 antikoerper, CLCN3 antikoerper, fb78c02 antikoerper, wu:fb78c02 antikoerper, clc3 antikoerper, clc-3 antikoerper, chloride voltage-gated channel 3 antikoerper, chloride channel, voltage-sensitive 3 antikoerper, chloride channel 3 antikoerper, chloride channel protein 3 antikoerper, chloride channel, voltage-sensitive 3 S homeolog antikoerper, CLCN3 antikoerper, Clcn3 antikoerper, clcn3 antikoerper, PTRG_03131 antikoerper, BDBG_05668 antikoerper, MCYG_04420 antikoerper, clcn3.S antikoerper

Hintergrund: Clcn3 mediates the exchange of chloride ions against protons, and functions as an antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. It may play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could also help neuronal cells to establish short-term memory.

Gen-ID: 84360

NCBI Accession: NP_445815

UniProt: P51792