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Erythrocyte Ankyrin Antikörper (AA 1-1881) (HRP)

ANK1 Reaktivität: Human WB, IHC, ICC, IF Wirt: Maus Monoclonal S388A-10 HRP
Produktnummer ABIN2485534
  • Target Alle Erythrocyte Ankyrin (ANK1) Antikörper anzeigen
    Erythrocyte Ankyrin (ANK1) (Ankyrin 1, Erythrocytic (ANK1))
    Bindungsspezifität
    • 9
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    AA 1-1881
    Reaktivität
    • 23
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 11
    • 11
    • 1
    Maus
    Klonalität
    • 13
    • 10
    Monoklonal
    Konjugat
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Erythrocyte Ankyrin Antikörper ist konjugiert mit HRP
    Applikation
    • 21
    • 15
    • 10
    • 9
    • 5
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Spezifität
    Detects ~200 kDa. Does not cross-react with Ankyrin-B or Ankyrin-G.
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Protein G Purified
    Immunogen
    Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R
    Klon
    S388A-10
    Isotyp
    IgG2b
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  • Applikationshinweise
    • WB (1:1000)
    • optimal dilutions for assays should be determined by the user.
    Kommentare

    A 1:100 dilution of ABIN2485534 was sufficient for detection of Ankyrin R in 20 μg of mouse brain lysate by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Conjugated antibodies should be stored at 4°C
  • Target
    Erythrocyte Ankyrin (ANK1) (Ankyrin 1, Erythrocytic (ANK1))
    Andere Bezeichnung
    Ankyrin R (ANK1 Produkte)
    Synonyme
    CHANK1 antikoerper, wu:fa09h06 antikoerper, zgc:101835 antikoerper, ank antikoerper, sph1 antikoerper, sph2 antikoerper, ANK1 antikoerper, ANK antikoerper, SPH1 antikoerper, SPH2 antikoerper, Ank-1 antikoerper, nb antikoerper, pale antikoerper, ankyrin 1 antikoerper, ankyrin 1, erythrocytic a antikoerper, ankyrin 1 L homeolog antikoerper, ankyrin 1, erythrocytic antikoerper, ankyrin 1, erythroid antikoerper, ANK1 antikoerper, ank1a antikoerper, ank1 antikoerper, ank1.L antikoerper, Ank1 antikoerper
    Hintergrund
    Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral membrane proteins. This linkage is required to maintain the integrity of the plasma membranes and to anchor specific ion channels, ion exchangers and ion transporters in the plasma membrane. Ankyrin R, or Ank1, was first discovered in erythrocyres, but has since also been located in the brain and muscles. Mutations are associated with hereditary spehrocytosis and alzheimer's diease (2).
    Gen-ID
    286
    NCBI Accession
    NP_000028
    UniProt
    P16157
    Pathways
    Synaptic Membrane
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