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SPTBN4 Antikörper (AA 1621-1832) (PE)

SPTBN4 Reaktivität: Human IHC, WB, ICC, IF Wirt: Maus Monoclonal S393-2 PE
Produktnummer ABIN2485679
  • Target Alle SPTBN4 Antikörper anzeigen
    SPTBN4 (Spectrin Beta, Non-Erythrocytic 4 (SPTBN4))
    Bindungsspezifität
    • 10
    • 1
    • 1
    • 1
    AA 1621-1832
    Reaktivität
    • 13
    • 1
    • 1
    • 1
    Human
    Wirt
    • 11
    • 1
    • 1
    Maus
    Klonalität
    • 11
    • 2
    Monoklonal
    Konjugat
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SPTBN4 Antikörper ist konjugiert mit PE
    Applikation
    • 12
    • 12
    • 11
    • 9
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Spezifität
    Detects ~>200 kDa. Does not cross react with other Beta-spectrins
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Protein G Purified
    Immunogen
    Fusion protein amino acids 1621-1832 (C-terminal repeats 14 to 15) of human Beta4-spectrin
    Klon
    S393-2
    Isotyp
    IgG1
    Top Product
    Discover our top product SPTBN4 Primärantikörper
  • Applikationshinweise
    • WB (1:1000)
    • optimal dilutions for assays should be determined by the user.
    Kommentare

    A 1:100 dilution of ABIN2485679 was sufficient for detection of Beta 4 Spectrin in 20 μg of mouse brain lysate by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Conjugated antibodies should be stored at 4°C
  • Target
    SPTBN4 (Spectrin Beta, Non-Erythrocytic 4 (SPTBN4))
    Andere Bezeichnung
    beta 4 Spectrin (SPTBN4 Produkte)
    Synonyme
    qv antikoerper, dyn antikoerper, lnd antikoerper, SpbIV antikoerper, ROSA62 antikoerper, nmf261 antikoerper, nmf379 antikoerper, 1700022P15Rik antikoerper, 5830426A08Rik antikoerper, Spnb4 antikoerper, QV antikoerper, SPNB4 antikoerper, SPTBN3 antikoerper, spectrin beta, non-erythrocytic 4 antikoerper, spectrin, beta, non-erythrocytic 4 antikoerper, Sptbn4 antikoerper, SPTBN4 antikoerper
    Hintergrund
    Spectrin is the major constituent of the cytoskeletal network underlying the erthrocyte plasma membrane and determines cell shape, arrangement of transmembrane proteins and organization of organelles. It is expressed at very low levels in many tissues, with the strongest expression in the cerebellum, spinal cord, stomach, pituitary gland, liver, pancreas, salivary gland, kidney, bladder and heart (1). Spectrin beta 4 is a non-erythrocyte member, and is expressed in the brain and pancreatic islets and localisted to the nuclear matrix, cytoplasmic vesicles and PML nuclear bodies. Beta4 spectrins are also essential for membrane stability and the molecular organization of the nodes of Ranvier (2).
    Gen-ID
    57731
    NCBI Accession
    NP_066022
    UniProt
    Q9H254
    Pathways
    Sensory Perception of Sound, Regulation of Actin Filament Polymerization, Maintenance of Protein Location
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