GABRA1 Antikörper (Cytoplasmic Domain) (PE)
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- Target Alle GABRA1 Antikörper anzeigen
- GABRA1 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1))
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Bindungsspezifität
- AA 368-419, Cytoplasmic Domain
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser GABRA1 Antikörper ist konjugiert mit PE
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Spezifität
- Detects ~55 kDa. Does not cross-react with GABA A Receptor Alpha2 or other GABA-A Receptors based on KO validation data.
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Protein G Purified
- Immunogen
- Fusion protein amino acids 368-419 (last cytoplasmic domain before extracellular C-terminus) of human GABA A Receptor Alpha5.
- Klon
- S415-24
- Isotyp
- IgG1
- Top Product
- Discover our top product GABRA1 Primärantikörper
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- Applikationshinweise
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- WB (1:1000)
- optimal dilutions for assays should be determined by the user.
- Kommentare
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A 1:100 dilution of ABIN2485768 was sufficient for detection of GABA-A R, Alpha5 in 20 μg of mouse brain lysate by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Conjugated antibodies should be stored at 4°C
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- Target
- GABRA1 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1))
- Andere Bezeichnung
- GABA A Receptor (GABRA1 Produkte)
- Synonyme
- ECA4 antikoerper, EJM antikoerper, EJM5 antikoerper, zgc:153566 antikoerper, Gabra-1 antikoerper, gamma-aminobutyric acid type A receptor alpha1 subunit antikoerper, gamma-aminobutyric acid (GABA) A receptor, alpha 1 antikoerper, gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 antikoerper, gamma-aminobutyric acid receptor subunit alpha-1 antikoerper, GABRA1 antikoerper, Gabra1 antikoerper, gabra1 antikoerper, LOC100653509 antikoerper
- Hintergrund
- The GABA A Receptor is a member of the superfamily of fast acting ligand-gated ion channels. The individual subunits of these receptors have similar sequences and structural features (1). GABA-A receptors are the major fast inhibitory neurotransmitter gated ion channels in the brain (2). Recent research shows their usage in investigating side effects of drugs and the effects of learning and memory. Inverse agonists of the Alpha5 subunit may be useful in the treatment of Alzheimer's Disease (3).
- Gen-ID
- 2558
- NCBI Accession
- NP_000801
- UniProt
- P31644
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