Aquaporin 4 Antikörper (C-Term) (Atto 488)
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- Target Alle Aquaporin 4 (AQP4) Antikörper anzeigen
- Aquaporin 4 (AQP4)
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Bindungsspezifität
- C-Term
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Reaktivität
- Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Aquaporin 4 Antikörper ist konjugiert mit Atto 488
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Spezifität
- Detects ~35 kDa. May detect larger glycosylated bands ~50 kDa.
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Protein A Purified
- Immunogen
- Produced against the C-terminal peptide (Sequence N-CTKGSYMEVEDNRSQVETED) of rat aquaporin 4
- Top Product
- Discover our top product AQP4 Primärantikörper
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- Applikationshinweise
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- WB (1:2000)
- IHC (1:200)
- ICC/IF (1:400)
- optimal dilutions for assays should be determined by the user.
- Kommentare
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0.5 μg/ml of ABIN2486385 was sufficient for detection of aquaporin 4 in 10 μg of rat kidney tissue lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Conjugated antibodies should be stored at 4°C
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- Target
- Aquaporin 4 (AQP4)
- Andere Bezeichnung
- Aquaporin 4 (AQP4 Produkte)
- Synonyme
- zgc:100922 antikoerper, si:ch211-192k9.1 antikoerper, AQP4 antikoerper, LOC100232616 antikoerper, HMIWC2 antikoerper, MIWC antikoerper, WCH4 antikoerper, AQP-4 antikoerper, AQP4.M23 antikoerper, MIWC2 antikoerper, Miwc antikoerper, aquaporin-4 antikoerper, aquaporin 4 antikoerper, aquaporin 4 L homeolog antikoerper, aqp4 antikoerper, AQP4 antikoerper, aqp4.L antikoerper, Aqp4 antikoerper
- Hintergrund
- Aquaporins selectively conduct water molecules in and out of the cell, while preventing the passage of ions and other solutes. Known as water channels, they are integral membrane pore proteins (1, 2). Aquaporin 4 is constitutively expressed in the basolateral cell membrane of principal collecting duct cells in the kidney and provide a pathway for water to exit these cells (3). It is also expressed in astrocytes and is up regulated by direct insult to the CNS (4). Aquaporin 4 has been proposed as the primary autoimmune target in neuromyelitis optica ( 5, 6).
- Gen-ID
- 25293
- NCBI Accession
- NP_036957
- UniProt
- P47863
- Pathways
- Sensory Perception of Sound
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