Aquaporin 1 Antikörper (N-Term) (FITC)

Produktnummer ABIN2486445

Produktdetails anti-Aquaporin 1 Antikörper (FITC)

Target: Aquaporin 1 (AQP1) (Aquaporin 1 (Colton Blood Group) (AQP1))

Bindungsspezifität: N-Term

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Aquaporin 1 Antikörper ist konjugiert mit FITC

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: Detects ~28.5 kDa. May detect larger glycosylated bands ~35-50 kDa.

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Protein A Purified

Immunogen: Produced against the N-terminal peptide (sequence N-MASEFKKKLF) of rat Aquaporin 1

Anwendungsinformationen

Applikationshinweise:

• WB (1:2000)
• IHC (1:200)
• ICC/IF (1:400)
• optimal dilutions for assays should be determined by the user.

Kommentare:

0.5 μg/ml of ABIN2486445 was sufficient for detection of aquaporin 1 in 10 μg of rat kidney tissue lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Conjugated antibodies should be stored at 4°C

Details zu Aquaporin 1

Target: Aquaporin 1 (AQP1) (Aquaporin 1 (Colton Blood Group) (AQP1))

Andere Bezeichnung: Aquaporin 1 (AQP1 Produkte)

Synonyme: fj33g04 antikoerper, zgc:85890 antikoerper, wu:fj33g04 antikoerper, AQP1 antikoerper, CHIP28 antikoerper, AQP-CHIP antikoerper, CO antikoerper, AQP-1 antikoerper, CHIP29 antikoerper, aquaporin 1a (Colton blood group), tandem duplicate 1 antikoerper, aquaporin 1 antikoerper, aquaporin 1 (Colton blood group) antikoerper, aqp1a.1 antikoerper, AQP1 antikoerper, Aqp1 antikoerper

Hintergrund: Aquaporins selectively conduct water molecules in and out of the cell, while preventing the passage of ions and other solutes. Known as water channels, they are integral membrane pore proteins (1, 2). Aquarporin 1 is a widely expressed water channel, found in the basolateral and apical plasma membranes of the proximal tubes, the descending loop of Henel and in the descending portion of the vasa recta. Additionally it is found in red blood cells, vascular endothelium, gastrointestinal tract, sweat glands and lungs. It is not regulated by vasopressin (3).

Gen-ID: 25240

NCBI Accession: NP_036910

UniProt: P29975

Pathways: Hormone Transport