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CENPA Antikörper (Atto 594)

CENPA Reaktivität: Human WB, IF, ICC Wirt: Maus Monoclonal 5A7-2E11 Atto 594
Produktnummer ABIN2486488
  • Target Alle CENPA Antikörper anzeigen
    CENPA (Centromere Protein A (CENPA))
    Reaktivität
    • 72
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 59
    • 13
    Maus
    Klonalität
    • 59
    • 13
    Monoklonal
    Konjugat
    • 30
    • 6
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CENPA Antikörper ist konjugiert mit Atto 594
    Applikation
    • 54
    • 31
    • 16
    • 13
    • 13
    • 11
    • 10
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    Detects ~18 kDa. Recognizes Human CENP-A.
    Kreuzreaktivität
    Human
    Aufreinigung
    Protein G Purified
    Immunogen
    Synthetic peptide corresponding to a portion of human CENP-A
    Klon
    5A7-2E11
    Isotyp
    IgG1
    Top Product
    Discover our top product CENPA Primärantikörper
  • Applikationshinweise
    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    Kommentare

    1 μg/ml of ABIN2486488 was sufficient for detection of CENPA in 20 μg of U2OS cell lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Conjugated antibodies should be stored at 4°C
  • Target
    CENPA (Centromere Protein A (CENPA))
    Andere Bezeichnung
    CENPA (CENPA Produkte)
    Synonyme
    CENP-A antikoerper, CenH3 antikoerper, Cenp-A antikoerper, cenpx antikoerper, cenp-a antikoerper, sim2 antikoerper, Cenp-a antikoerper, RGD1563607 antikoerper, CENPA antikoerper, centromere protein A antikoerper, centromere protein-A antikoerper, centromeric histone-3 like protein antikoerper, centromere-specific histone H3 CENP-A antikoerper, cenp-A antikoerper, centromere protein A L homeolog antikoerper, histone H3-like centromeric protein A antikoerper, CENPA antikoerper, Cenpa antikoerper, CENP-A antikoerper, cenpa antikoerper, cenp-A antikoerper, cnp1 antikoerper, HAN_3g422 antikoerper, Cenp-a antikoerper, cenpa.L antikoerper, CMU_016480 antikoerper
    Hintergrund
    A replicated chromosome includes two kinetochores that control chromosome segregation during mitosis. The Centromere Protein-A, CENP-A, is a Histone H3-like protein that contains a C-terminal H3-like domain, which is required for centromere localization of CENP-A, and an antigenic N-terminal domain. CENP-A, originally isolated from HeLa cells, is essential for kinetochore targeting of CENP-C. In the presence of DNA CENP-A forms an octa-meric complex with histones H4, H2A, H2B. CENP-A specifically localizes to active centromeres and is a component of specialized centromeric nucleosomes, on which kinetochores are assembled. CENP-A is essential for nucleosomal packaging of centromeric DNA at interphase and functions as a centromere formation marker on the chromosome.
    Gen-ID
    1058
    NCBI Accession
    NP_001035891
    UniProt
    P49450
    Pathways
    Chromatin Binding, Maintenance of Protein Location
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