Ras Protein-Specific Guanine Nucleotide-Releasing Factor 2 (RASGRF2) (AA 20-120) Antikörper (Biotin)

Produktnummer ABIN2559497

Produktdetails

Target: Ras Protein-Specific Guanine Nucleotide-Releasing Factor 2 (RASGRF2)

Bindungsspezifität: AA 20-120

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Cow,Sheep

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GRF2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Antigendetails

Target: Ras Protein-Specific Guanine Nucleotide-Releasing Factor 2 (RASGRF2)

Andere Bezeichnung: GRF2 (RASGRF2 Produkte)

Synonyme: 6330417G04Rik antikoerper, AW048350 antikoerper, Grf2 antikoerper, Ras-GRF2 antikoerper, rasgrf2 antikoerper, rasgrf2-2 antikoerper, GRF2 antikoerper, RAS-GRF2 antikoerper, RAS protein-specific guanine nucleotide-releasing factor 2 antikoerper, Ras protein-specific guanine nucleotide-releasing factor 2b antikoerper, Ras protein specific guanine nucleotide releasing factor 2 antikoerper, Rasgrf2 antikoerper, rasgrf2b antikoerper, RASGRF2 antikoerper

Hintergrund:

Synonyms: GRF2, RAS-GRF2, Ras-specific guanine nucleotide-releasing factor 2, Ras guanine nucleotide exchange factor 2, RASGRF2

Background: Functions as a calcium-regulated nucleotide exchange factor activating both Ras and RAC1 through the exchange of bound GDP for GTP. Preferentially activates HRAS in vivo compared to RRAS based on their different types of prenylation. Functions in synaptic plasticity by contributing to the induction of long term potentiation.

Gen-ID: 5924

UniProt: O14827

Pathways: Neurotrophin Signalübertragung