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TMEM30A Antikörper (AA 251-350)

TMEM30A Reaktivität: Human, Maus, Ratte WB, IF (cc), IF (p), ELISA, IHC (p), IHC (fro), ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2559505
  • Target Alle TMEM30A Antikörper anzeigen
    TMEM30A (Transmembrane Protein 30A (TMEM30A))
    Bindungsspezifität
    • 14
    • 1
    • 1
    • 1
    • 1
    AA 251-350
    Reaktivität
    • 25
    • 25
    • 25
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 25
    Kaninchen
    Klonalität
    • 25
    Polyklonal
    Konjugat
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TMEM30A Antikörper ist unkonjugiert
    Applikation
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    Kreuzreaktivität
    Human, Maus, Ratte
    Homologie
    Cow,Pig,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Transmembrane protein 30A
    Isotyp
    IgG
    Top Product
    Discover our top product TMEM30A Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    TMEM30A (Transmembrane Protein 30A (TMEM30A))
    Andere Bezeichnung
    Transmembrane protein 30A (TMEM30A Produkte)
    Synonyme
    tmem30a antikoerper, wu:fj66b08 antikoerper, zgc:91877 antikoerper, fi23a10 antikoerper, wu:fb15c10 antikoerper, wu:fi23a10 antikoerper, zgc:55379 antikoerper, zgc:77655 antikoerper, cg9947 antikoerper, MGC53259 antikoerper, MGC75889 antikoerper, CDC50A antikoerper, DKFZp459A091 antikoerper, DKFZp459D097 antikoerper, DKFZp459B0431 antikoerper, C6orf67 antikoerper, 2010200I23Rik antikoerper, AW540225 antikoerper, Cdc50a antikoerper, D9Wsu20e antikoerper, transmembrane protein 30Aa antikoerper, transmembrane protein 30A antikoerper, transmembrane protein 30Ab antikoerper, transmembrane protein 30A L homeolog antikoerper, tmem30aa antikoerper, TMEM30A antikoerper, tmem30ab antikoerper, tmem30a.L antikoerper, tmem30a antikoerper, LOAG_03933 antikoerper, Tmem30a antikoerper
    Hintergrund

    Synonyms: CDC50A, C6orf67, Cell cycle control protein 50A, P4-ATPase flippase complex beta subunit TMEM30A, Transmembrane protein 30A, TMEM30A

    Background: Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate. Required for the proper folding, assembly and ER to Golgi exit of the ATP8A2:TMEM30A flippase complex. ATP8A2:TMEM30A may be involved in regulation of neurite outgrowth, and, reconstituted to liposomes, predomiminantly transports phosphatidylserine (PS) and to a lesser extent phosphatidylethanolamine (PE). The ATP8A1:TMEM30A flippase complex seems to play a role in regulation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine (PE) at the plasma membrane. Required for the formation of the ATP8A2, ATP8B1 and ATP8B2 P-type ATPAse intermediate phosphoenzymes. Involved in uptake of platelet-activating factor (PAF), synthetic drug alkylphospholipid edelfosine, and, probably in association with ATP8B1, of perifosine. Also mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2, ATP8B4, ATP10A, ATP10B, ATP10D, ATP11A, ATP11B and ATP11C from the ER to other membrane localizations.

    Gen-ID
    55754
    UniProt
    Q9NV96
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