CHMP2A Antikörper (AA 1-100) (AbBy Fluor® 488)
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- Target Alle CHMP2A Antikörper anzeigen
- CHMP2A (Charged Multivesicular Body Protein 2A (CHMP2A))
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Bindungsspezifität
- AA 1-100
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Reaktivität
- Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CHMP2A Antikörper ist konjugiert mit AbBy Fluor® 488
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Ratte
- Homologie
- Human,Mouse,Dog,Sheep
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CHMP2A
- Isotyp
- IgG
- Top Product
- Discover our top product CHMP2A Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- CHMP2A (Charged Multivesicular Body Protein 2A (CHMP2A))
- Andere Bezeichnung
- CHMP2A (CHMP2A Produkte)
- Synonyme
- BC-2 antikoerper, BC2 antikoerper, CHMP2 antikoerper, VPS2 antikoerper, VPS2A antikoerper, 1500016L11Rik antikoerper, RGD1305050 antikoerper, bc-2 antikoerper, bc2 antikoerper, chmp2 antikoerper, vps2 antikoerper, vps2a antikoerper, fj10d05 antikoerper, wu:fi18h03 antikoerper, wu:fj10d05 antikoerper, zgc:55361 antikoerper, charged multivesicular body protein 2a antikoerper, charged multivesicular body protein 2A antikoerper, Charged multivesicular body protein 2a antikoerper, charged multivesicular body protein 2A L homeolog antikoerper, ATEG_06167 antikoerper, LOC5570080 antikoerper, EDI_289610 antikoerper, PTRG_09933 antikoerper, NAEGRDRAFT_39042 antikoerper, PITG_17335 antikoerper, Tsp_00033 antikoerper, LOC100284170 antikoerper, LOC100284688 antikoerper, chm2a antikoerper, chmp2a antikoerper, CHMP2A antikoerper, Chmp2a antikoerper, chmp2a.L antikoerper
- Hintergrund
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Synonyms: BC2, BC-2, VPS2, CHMP2, VPS2A, Charged multivesicular body protein 2a, Chromatin-modifying protein 2a, CHMP2a, Putative breast adenocarcinoma marker BC-2, Vacuolar protein sorting-associated protein 2-1, Vps2-1, hVps2-1
Background: Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in HIV-1 p6- and p9-dependent virus release.
- Gen-ID
- 27243
- UniProt
- O43633
- Pathways
- SARS-CoV-2 Protein Interaktom
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