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Leptin Receptor Antikörper (AA 901-1000) (PE)

LEPR Reaktivität: Human, Maus, Ratte, Schwein WB, FACS Wirt: Kaninchen Polyclonal PE
Produktnummer ABIN2559727
  • Target Alle Leptin Receptor (LEPR) Antikörper anzeigen
    Leptin Receptor (LEPR)
    Bindungsspezifität
    • 16
    • 15
    • 10
    • 9
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 901-1000
    Reaktivität
    • 106
    • 70
    • 48
    • 18
    • 12
    • 3
    • 3
    • 3
    Human, Maus, Ratte, Schwein
    Wirt
    • 110
    • 14
    • 2
    • 1
    • 1
    • 1
    Kaninchen
    Klonalität
    • 106
    • 23
    Polyklonal
    Konjugat
    • 48
    • 11
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Dieser Leptin Receptor Antikörper ist konjugiert mit PE
    Applikation
    • 80
    • 41
    • 36
    • 34
    • 26
    • 25
    • 16
    • 11
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Spezifität
    This antibody will recognize the Isoform B variant only
    Kreuzreaktivität
    Human, Maus, Schwein, Ratte
    Homologie
    Dog,Cow,Sheep
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Leptin receptor:901-1000/1165
    Isotyp
    IgG
    Top Product
    Discover our top product LEPR Primärantikörper
  • Applikationshinweise
    FCM 1:20-100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Goto, Kaneko, Sato, Otsuka, Yamamoto, Goto, Yamamoto, Yamamoto, Kawachi, Madaio, Narita: "Leptin deficiency down-regulates IL-23 production in glomerular podocytes resulting in an attenuated immune response in nephrotoxic serum nephritis." in: International immunology, Vol. 28, Issue 4, pp. 197-208, (2016) (PubMed).

  • Target
    Leptin Receptor (LEPR)
    Andere Bezeichnung
    Leptin receptor (Isoform B) (LEPR Produkte)
    Synonyme
    CD295 antikoerper, LEP-R antikoerper, LEPRD antikoerper, OB-R antikoerper, OBR antikoerper, obr antikoerper, cd295 antikoerper, ob-rb antikoerper, Fa antikoerper, LEPROT antikoerper, Leprb antikoerper, Modb1 antikoerper, OB-RGRP antikoerper, Obr antikoerper, db antikoerper, diabetes antikoerper, obese-like antikoerper, obl antikoerper, ObRb antikoerper, Ob-R antikoerper, Ob-RM antikoerper, lepr antikoerper, leptin receptor antikoerper, leptin receptor S homeolog antikoerper, LEPR antikoerper, lepr antikoerper, Lepr antikoerper, lepr.S antikoerper
    Hintergrund

    Synonyms: OBR, OB-R, CD295, LEP-R, LEPRD, Leptin receptor, HuB219, OB receptor, LEPR, DB, LEPR_MOUSE

    Background: Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway (By similarity).

    Gen-ID
    3953
    UniProt
    P48357
    Pathways
    JAK-STAT Signalweg, AMPK Signaling, Feeding Behaviour
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