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CD3 epsilon Antikörper (PE-Cy7)
CD3E
Reaktivität: Maus
FACS
Wirt: Hamster
Monoclonal
145-2C11
PE-Cy7
Produktnummer ABIN2567612
Produktdetails anti-CD3 epsilon Antikörper (PE-Cy7)
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Target
Alle CD3 epsilon (CD3E) Antikörper anzeigen
CD3 epsilon (CD3E)
Reaktivität
Alle Reaktivitäten für CD3 epsilon Antikörper
Maus
Wirt
Alle Wirte für CD3 epsilon Antikörper
Hamster
Klonalität
Alle Klonalitäten für CD3 epsilon Antikörper
Monoklonal
Konjugat
Alle Konjugate für CD3 epsilon Antikörper
Dieser CD3 epsilon Antikörper ist konjugiert mit PE-Cy7
Applikation
Alle Applikationen für CD3 epsilon Antikörper
Flow Cytometry (FACS)
Spezifität
The 145-2C11 monoclonal antibody reacts with mouse CD3e, the 20 kDa ε chain of the TCR complex.
Aufreinigung
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Klon
145-2C11
Isotyp
IgG
Top Product
Discover our top product CD3E Primärantikörper
Alternativen
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anti-CD3 epsilon (CD3E) (AA 156-168), (Cytoplasmic Domain) antibody
CD3E
Reaktivität: Human, Ratte, Schwein, Kaninchen, Rind (Kuh), Pferd, Meerschweinchen, Huhn
FACS, WB, IF
Wirt: Maus
Monoclonal
PC3-188A
unconjugated
Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
0.2 mg/mL
Buffer
Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Lagerung
4 °C
Informationen zur Lagerung
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Details zu CD3 epsilon
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Target
CD3 epsilon (CD3E)
Andere Bezeichnung
CD3e (CD3E Produkte )
Synonyme
cd3e antikoerper, CD3E antikoerper, t3e antikoerper, tcre antikoerper, AI504783 antikoerper, CD3 antikoerper, CD3epsilon antikoerper, T3e antikoerper, T3E antikoerper, TCRE antikoerper, CD3e molecule antikoerper, CD3 antigen, epsilon polypeptide antikoerper, cd3e antikoerper, CD3E antikoerper, Cd3e antikoerper
Hintergrund
The 145-2C11 monoclonal antibody reacts with mouse CD3e, the 20 kDa ε chain of the TCR complex. Together with the γ and δ subunits of CD3, the ε subunits are involved in the assembly, trafficking, and surface expression of T-cell receptor complex. CD3 is expressed on thymocytes, mature T cells, and natural killer T cells, and the ε chain enhances the antigen recognition.The 145-2C11 antibody binds to the TCR complex and, depending on the conditions, initiates T cells activation, proliferation, and apoptosis. The soluble antibody seems to block lysis of target cells by antigen-specific cytotoxic T lymphocytes. The 145-2C11 antibody does not cross-react with the rat leukocytes, and it is used as a phenotypic marker for mouse T lymphocytes.
Gen-ID
12501
UniProt
P22646
Pathways
T-Zell Rezeptor Signalweg , CXCR4-mediated Signaling Events , Ubiquitin Proteasome Pathway
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