CTXB Antikörper
CTXB
Reaktivität: Vibrio cholerae
EIA, WB
Wirt: Maus
Monoclonal
B040M
unconjugated
-
- Target Alle CTXB Produkte
- CTXB (CtxB Gene Product (CTXB))
- Reaktivität
- Vibrio cholerae
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser CTXB Antikörper ist unkonjugiert
-
Applikation
- Enzyme Immunoassay (EIA), Western Blotting (WB)
- Spezifität
- Reacts with cholera toxin beta subunit.
- Produktmerkmale
- Synonyms: Cholera enterotoxin B chain, Cholera enterotoxin gamma chain, Choleragenoid, ctxB, toxB,VC_1456
- Aufreinigung
- Protein A Sepharose chromatography
- Reinheit
- > 90 % pure (SDS-PAGE)
- Immunogen
- Purified beta subunit of cholera toxin. Hybridization of Sp2/0 myeloma cells with spleencells from Balb/c mice.
- Klon
- B040M
- Isotyp
- IgG2a
-
-
- Applikationshinweise
-
ELISA. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Buffer
- PBS, pH 7.4 containing 0.09 % Sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
-
Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
Shelf life: one year from despatch. - Haltbarkeit
- 12 months
-
- Target
- CTXB (CtxB Gene Product (CTXB))
- Andere Bezeichnung
- Cholera Enterotoxin Subunit B (CTXB Produkte)
- Hintergrund
- The B subunit of cholera toxin (CtxB) binds to a GM1-ganglioside receptor, a ubiquitous glycolipid cell surface receptor. This binding is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin A subunit into cells. The beta chain has no toxic activity by itself. The holotoxin consists of a pentameric ring of B subunits whose central pore is occupied by the A subunit. The A subunit contains two chains, A1 and A2, linked by a disulfide bridge. The A subunit (and Cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.Synonyms: Cholera enterotoxin B chain, Cholera enterotoxin gamma chain, Choleragenoid, VC_1456, ctxB, toxB
- Gen-ID
- 2613962
- UniProt
- P01556
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