FE
Reaktivität: Human
ELISA, LF
Wirt: Huhn
Polyclonal
unconjugated
Applikationshinweise
ELISA. Recommended Pairs for Sandwich ImmunoassayCapture/Detection: ABIN263731 / ABIN263729ABIN263733 / ABIN263729 Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
5.37 mg/mL (OD280nm, E0.1% = 1.4)
Buffer
10 mM Phosphate, pH 7.4 containing 150 mM Sodium Chloride, 0.09 % Sodium Azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one week or (in aliquots) at -40 °C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Ferritin is a ubiquitous and highly conserved protein which plays a major role in iron homeostasis by sequestering and storing iron in a non-toxic and soluble form. It forms a holoenzyme of ~450 kDa, consisting of 24 subunits of two types, H (heavy, 21 kDa) and L (light, 19 kDa), and is capable of storing up to 4,500 atoms of ferric iron. Depending on the tissue type and physiological status of the cell, the ratio of H to L subunits in ferritin can vary widely. Ferritin is found in the liver, spleen, kidney and heart, with smaller amounts being found in blood. Serum ferritin levels serve as an indicator of the amount of iron stored in the body. Serum ferritin is the most sensitive test for anaemia, and is also used as a marker for restless leg syndrome, hemochromatosis and porphyria. As ferritin is an acute-phase reactant, it is often elevated during infection. Defects in ferritin proteins are associated with several neurodegenerative diseases.Synonyms: FTH, FTL, Ferritin H subunit, Ferritin L subunit