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Calpain Antikörper (Agarose Beads)

Reaktivität: Human IP Wirt: Maus Monoclonal 28F3 Agarose Beads
Produktnummer ABIN264386
  • Target Alle Calpain Produkte
    Calpain
    Reaktivität
    • 4
    • 3
    • 1
    • 1
    • 1
    Human
    Wirt
    • 4
    • 3
    Maus
    Klonalität
    • 4
    • 3
    Monoklonal
    Konjugat
    • 5
    • 1
    • 1
    Dieser Calpain Antikörper ist konjugiert mit Agarose Beads
    Applikation
    • 7
    • 4
    • 3
    • 1
    • 1
    Immunoprecipitation (IP)
    Produktmerkmale
    Synonyms: CAPN2, CANPL2, CANP-2, CAPN1, CANPL1, CANP1
    Aufreinigung
    Standard chromatographic techniques.
    Immunogen
    Calpain purified from human placenta.
    Klon
    28F3
    Isotyp
    IgG1
  • Applikationshinweise
    ELISA: 0.5-1 μg/mL. Western blot: 0.5-1 μg/mL. Immunoprecipitation of both the native and denatured protein: 1-2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    20 mM Sodium Phosphate, pH 7.5, 150 mM Sodium Chloride, 50 % Glycerol and 3 mM Sodium Azide as preservative.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store the antibody at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: One year from despatch.
    Haltbarkeit
    12 months
  • Target
    Calpain
    Abstract
    Calpain Produkte
    Synonyme
    CG18152 antikoerper, CG7563 antikoerper, Dmel\\CG7563 antikoerper, EST C antikoerper, calpain antikoerper, Tb08.28A12.350 antikoerper, Calpain-A antikoerper, hypothetical protein antikoerper, calpain 11 antikoerper, calpain antikoerper, CalpA antikoerper, T11A5.6 antikoerper, CAPN11 antikoerper, Tb927.8.8330 antikoerper
    Hintergrund
    The calpains are calcium-dependent cysteine proteases that are widely expressed in mammalian systems. Both m-calpain (calpain II) and -calpain (calpain I) are composed of an 80 kD subunit and a 30 kD subunit. Whereas the 30 kDa subunit is shared by both enzymes, the larger catalytic subunits are different and exhibit the distinct Ca ++ requirements that are suggested by their names. Whereas m-calpain requires millimolar ( mM) levels of calcium, u-calpain is active at micromolar (uM) concentrations of Ca++. In addition to the ubiquitously expressed m- and u-calpains, some tissue-specific calpains have been identified. The calpains appear to serve multiple physiological roles, and ideas concerning the functions of these enzymes are in a state of rapid flux.Synonyms: CANP-2, CANP1, CANPL1, CANPL2, CAPN1, CAPN2
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