KRT14 Antikörper
-
- Target Alle KRT14 Antikörper anzeigen
- KRT14 (Keratin 14 (KRT14))
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser KRT14 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Spezifität
- This antibody reacts specifically with Human Cytokeratin-14 (50 kDa) by Immunoblotting. Does not react with other Cytokeratins or other proteins.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human.
- Produktmerkmale
- Synonyms: Cytokeratin-14, CK14, Keratin 14, K14, KRT14, Keratin Type I Cytoskeletal 14
- Aufreinigung
- Protein A/G Chromatography
- Immunogen
- Synthetic peptide conjugated to KLH corresponding to thecarboxy terminal sequence of human cytokeratin 14(KVVSTHEQVLRTKN)Genename: KRT14
- Klon
- DE-SPK14
- Isotyp
- IgG2b
- Top Product
- Discover our top product KRT14 Primärantikörper
-
-
- Applikationshinweise
-
Western Blot: Detects human cytokeratin 14 at 50 kDa. Immunohistochemistry (Frozen Sections): It provides a positive reaction on basal cells ofnon-keratinizing stratified epithelia, basal cells and suprabasal cells of the epidermis andgingiva, myoepithelial cells and squamous cell carcinomas. Not suitable for use in Paraffin embedded tissues.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 1 mg/mL
- Buffer
- PBS, 0.08 % Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
-
Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch. - Haltbarkeit
- 12 months
-
- Target
- KRT14 (Keratin 14 (KRT14))
- Andere Bezeichnung
- Cytokeratin 14 (KRT14 Produkte)
- Synonyme
- CK14 antikoerper, EBS3 antikoerper, EBS4 antikoerper, K14 antikoerper, NFJ antikoerper, AI626930 antikoerper, Krt-1.14 antikoerper, Krt1-14 antikoerper, Ka14 antikoerper, ouro2 antikoerper, keratin 14 antikoerper, keratin 14, type I L homeolog antikoerper, KRT14 antikoerper, Krt14 antikoerper, krt14.L antikoerper
- Hintergrund
- Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (ie., skin) and non-keratinizing cells (ie., mesothelial cells). Although not a traditional marker for endothelial cells, cytokeratins have also been found in some microvascular endothelial cells. Atleast 20 different cytokeratins (CK) in the molecular range of 40-70 kDa and isoelectric points of 5-8.5 can be identified using two dimensional gel electrophoresis. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Monoclonal antibodies to cytokeratin proteins can be useful markers for tumor identification and classification. Keratin 14 is a member of the keratin family, the most diverse group of intermediate filaments. It is usually found as a heterotetramer with two molecules of keratin 5, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. Keratin 14 has been studied as a prognostic marker in breast cancer.Synonyms: CK14, Cytokeratin-14, K14, KRT14, Keratin 14, Keratin Type I Cytoskeletal 14
- Gen-ID
- 3861
- UniProt
- P02533
-