ADRA2B Antikörper

Produktnummer ABIN264463

Produktdetails anti-ADRA2B Antikörper

Target: ADRA2B (Adrenergic, alpha-2B-, Receptor (ADRA2B))

Reaktivität: Ratte, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ADRA2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktmerkmale: Synonyms: ADRA2B, ADRA2L1, ADRA2RL1, Alpha-2B adrenoreceptor, Alpha-2B adrenoceptor

Aufreinigung: Purified

Immunogen: Antibody raised to synthetic peptide internal sequence corresponding to the thirdintracellular loop of rat alpha 2b adrenergic receptor.

Klon: 5G10

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western blot (1-5 μg/mL). Immunohistochemistry. Positive Control/Tissue Expression: MDCK cells transfected with rat alpha2B adrenergicreceptors.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.08 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.

Haltbarkeit: 12 months

Details zu ADRA2B

Target: ADRA2B (Adrenergic, alpha-2B-, Receptor (ADRA2B))

Andere Bezeichnung: alpha-2B Adrenergic Receptor (ADRA2B Produkte)

Hintergrund: The rat alpha 2b adrenergic receptor is a G protein coupled receptor which acts through Gi2 and is responsible for Cellular communication and signal transduction. These receptors are linked to pertussis toxin-sensitive G proteins. Agonist binding leads to inhibition of adenylyl cyclase, inhibition of Ca(2+) channels and activation of K(+) channels. Recently, three distinct subtypes of alpha(2)-AR were described, alpha(2A)-AR, alpha(2B)-AR and alpha(2C)-AR. At present, it is unknown which of these alpha(2)-AR subtype(s) may regulate insulin secretion.Synonyms: ADRA2B, ADRA2L1, ADRA2RL1, Alpha-2B adrenoceptor, Alpha-2B adrenoreceptor

Gen-ID: 24174

UniProt: P19328

Pathways: EGFR Signaling Pathway, cAMP Metabolic Process