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Acetylated Lysine Antikörper (acetylated)

WB, IP, IF, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN264880
  • Target Alle Acetylated Lysine Produkte
    Acetylated Lysine
    Bindungsspezifität
    • 6
    • 1
    • 1
    acetylated
    Reaktivität
    Bitte anfragen
    Wirt
    • 28
    • 22
    Kaninchen
    Klonalität
    • 26
    • 23
    Polyklonal
    Konjugat
    • 21
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser Acetylated Lysine Antikörper ist unkonjugiert
    Applikation
    • 47
    • 38
    • 33
    • 18
    • 18
    • 15
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Aufreinigung
    Affinity Chromatography
    Immunogen
    Acetylated KLH Conjugated
    Isotyp
    IgG
  • Applikationshinweise
    Western blot (6). Immunoprecipitation (7). ELISA. Immonoflourescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS, 0.09 % Sodium Azide, 50 % Glycerol
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Acetylated Lysine
    Abstract
    Acetylated Lysine Produkte
    Synonyme
    C-K-RAS antikoerper, CFC2 antikoerper, K-RAS2A antikoerper, K-RAS2B antikoerper, K-RAS4A antikoerper, K-RAS4B antikoerper, KI-RAS antikoerper, KRAS1 antikoerper, KRAS2 antikoerper, NS antikoerper, NS3 antikoerper, RASK2 antikoerper, KRAS proto-oncogene, GTPase antikoerper, KRAS antikoerper
    Substanzklasse
    Chemical
    Hintergrund
    Post-translational modifications of proteins play critical roles in the regulation and function of many known biological processes. Proteins can be post-translationally modified in many different ways, and a common posttranscriptional modification of Lysine involves acetylation (1). The conserved amino-terminal domains of the four core histones (H2A, H2B, H3 and H4) contain lysines that are acetylated by histone acetyltransferases (HATs) and deacetylated by histone deacetylases (HDACs) (2). Protein posttranslational reversible lysine N?-acetylation and deacetylation have been recognized as an emerging intracellular signaling mechanism that plays critical roles in regulating gene transcription, cell-cycle progression, apoptosis, DNA repair, and cytoskeletal organization (3). The regulation of protein acetylation status is impaired in the pathologies of cancer and polyglutamine diseases (4), and HDACs have become promising targets for anticancer drugs currently in development (5).Synonyms: AcK, acetyl Lysine, acetyl-Lysine
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