Immunoprecipitation: 1 - 10 μg/mL, of the catalyticaly active form of SAP kinase, in vitrokinase assay. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target
MAPK8/9/10
(Mitogen-Activated Protein Kinase 8/9/10 (MAPK8/9/10))
SAP kinase detects native SAP kinase by immunoprecipitation in rat and human (HeLa) cells. SAP kinase is induced by stress agonists such as UV irradiation, heat shock and inflammatory cytokines. These stress stimuli result in the phosphorylation of and enzymatic activation of Stress Activated Protein Kinases (SAP kinases). Three SAP kinase gene are known to exist, a, b and g , which are differentially spliced giving 10 gene products in total.Synonyms: 2, 3, JNK1, MAPK8/9/10, SAPK alpha beta gamma